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Table 2 Diagnostic accuracy of screening tools to expedite assessment of frailty in people receiving haemodialysis

From: Screening tools to expedite assessment of frailty in people receiving haemodialysis: a diagnostic accuracy study

Screening tools AUC (95% CI) P-value Gini-I K-S Cut-off Prevalence, n (%) SENS SPEC PPV NPV LR+ LR-
Handgrip (Kg) 0.71 (0.59–0.83) 0.001 0.42 0.36 ≤ 21.17 18 (23.7) 90% 46% 0.49 0.89 1.67 0.22
Gait speed (m/s) 0.89 (0.81–0.98) < 0.001 0.78 0.68 ≤ 0.85 38 (50.7) 75% 93% 0.86 0.87 10.14 0.27
TUG (s) 0.90 (0.80–0.99) < 0.001 0.79 0.74 ≥ 10.88 30 (40.5) 89% 85% 0.76 0.93 6.06 0.13
STS-5 (s) 0.86 (0.75–0.96) <0.001 0.71 0.64 ≥ 15.65 30 (42.3) 87% 77% 0.64 0.93 3.80 0.17
SF-36 PF (score) 0.78 (0.67–0.89) < 0.001 0.56 0.49 ≤ 42.5 40 (54.1) 64% 85% 0.71 0.80 4.31 0.42
SF-36 PCS (score) 0.76 (0.64–0.88) < 0.001 0.52 0.47 ≤ 32.3 27 (37) 80% 67% 0.59 0.85 2.41 0.29
IPAQ (METs/min/week) 0.84 (0.75–0.94) < 0.001 0.68 0.61 ≤ 99 25 (32.9) 90% 71% 0.64 0.92 3.13 0.15
FES (score) 0.84 (0.74–0.94) < 0.001 0.68 0.61 ≥ 21 33 (43.4) 82% 79% 0.69 0.88 3.95 0.23
  1. Abbreviations AUC Area under the curve, CI Confidence interval, Gini-I Gini Index, K-S KS statistic, SENS Sensitivity, SPEC specificity, PPV Positive predictive value, NPV Negative predictive value, LR+ Positive likelihood ratio, LR- Negative likelihood ratio, TUG Timed up and go test, STS-5 Five-seconds sit to stand test, SF-36 PF Physical function score of SF-36 questionnaire, SF-36 PCS Physical composite scale of SF-36 questionnaire, IPAQ International physical activity questionnaire (short format), FES Tinetti falls efficacy scale