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Table 3 Patient characteristics by quartile categorization

From: Neutrophil-lymphocyte ratio as a predictor of delirium in older internal medicine patients: a prospective cohort study

Characteristic NLR Quartiles P-value a
< 2.055
(n = 185)
2.055–3.110 (n = 185) 3.111–5.735 (n = 185) > 5.735 (n = 185)
Age (years), median (IQR) 83 (79–86) 83 (76–86) 85 (80–88) 85 (81–88) < 0.001
Male sex, n (%) 126 (68.1) 125 (67.6) 144 (77.8) 132 (71.4) 0.110
Living alone, n (%) 8 (4.3) 6 (3.2) 10 (5.4) 7 (3.8) 0.758
Married, n (%) 160 (86.5) 155 (83.8) 153 (82.7) 142 (76.8) 0.091
Education, n (%)      
Illiteracy or primary school 17 (9.2) 31 (16.8) 27 (14.6) 36 (19.5)  
Middle school 24 (13.0) 31 (16.8) 39 (21.1) 39 (21.1) 0.002
High school or above 144 (77.8) 123 (66.5) 119 (64.3) 110 (59.5)  
Alcohol abuse, n (%) 149 (20.1) 84 (19.5) 65(21.0) 33 (17.8) 0.285
Smoker, n (%) 57 (30.8) 71 (38.4) 72 (38.9) 83 (44.9) 0.050
Vision impairment, n (%) 61 (33.0) 57 (30.8) 66 (35.7) 59 (31.9) 0.778
Hearing impairment, n (%) 53 (28.6) 58 (31.4) 58 (31.4) 60 (32.4) 0.879
Cognitive impairment, n (%) 33 (17.8) 41 (22.2) 68 (36.8) 92 (49.7) < 0.001
Emergency admission, n (%) 5 (2.7) 14 (7.6) 27 (14.6) 51 (27.6) < 0.001
Barthel index, median (IQR) 95 (75–100) 90 (65–100) 80 (47–95) 55 (35–80) < 0.001
CCI, n (%)      
Mild (≤ 2) 152 (82.2) 151 (81.6) 141 (76.2) 122 (65.9)  
Moderate (3–4) 28 (15.1) 28 (15.1) 38 (20.5) 42 (22.7) < 0.001
Severe (≥ 5) 5 (2.7) 6 (3.2) 6 (3.2) 21 (11.4)  
NLR, median (IQR) 1.6 (1.3–1.8) 2.6 (2.3–2.8) 4.0 (3.5–4.9) 8.3 (7.1–12.3) < 0.001
Neutrophil count (109/L), median (IQR) 2.9 (2.3–3.6) 3.7 (3.0-4.5) 4.7 (3.8–5.4) 6.6 (5.3-9.0) < 0.001
Lymphocyte count (109/L), median (IQR) 1.9 (1.5–2.4) 1.5 (1.2–1.8) 1.2 (0.9–1.4) 0.7 (0.6-1.0) < 0.001
Delirium, n (%) 8 (4.3) 10 (5.4) 37 (20.0) 46 (24.9) < 0.001
  1. NLR neutrophil-lymphocyte ratio, CCI Charlson Comorbidity Index, IQR interquartile range
  2. Notes: aP values according Kruskall-Wallis or Chi-square tests