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Table 1 Senescent T cells and Myeloid Derived Suppressor Cell subtypes markers

From: A randomized clinical study on the impact of Comprehensive Geriatric Assessment (CGA) based interventions on the quality of life of elderly, frail, onco-hematologic patients candidate to anticancer therapy: protocol of the ONCO-Aging study

Type of cell

Markers

Senescent T cell

CD28- (co-stimulatory)

CD57+ (senescence)

KLRG1+ (senescence)

p16INK4 (senescence)

p21Cip/Waf1 (senescence)

M-MDSC

CD14+ (monocyte differentiation)

CD11b+ (migration)

HLA-DRlow/− (proliferation)

CD15- (migration)

PMN-MDSC

CD14- (monocyte differentiation)

CD11b+ (migration)

HLA-DR+ (proliferation)

CD15+ (migration)

CD33int (adhesion)

LOX-1+ (proliferation)

  1. Legend-CD Cluster of Differentiation; PMN-MDSC PolyMorphoNucler-Myeloid Derived Suppressor Cell; M Monocytic-Myeloid Derived Suppressor Cell; LOX-1 Lectin-like OXidized low-density lipoprotein (LDL) receptor-1