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Table 1 Senescent T cells and Myeloid Derived Suppressor Cell subtypes markers

From: A randomized clinical study on the impact of Comprehensive Geriatric Assessment (CGA) based interventions on the quality of life of elderly, frail, onco-hematologic patients candidate to anticancer therapy: protocol of the ONCO-Aging study

Type of cell Markers
Senescent T cell CD28- (co-stimulatory)
CD57+ (senescence)
KLRG1+ (senescence)
p16INK4 (senescence)
p21Cip/Waf1 (senescence)
M-MDSC CD14+ (monocyte differentiation)
CD11b+ (migration)
HLA-DRlow/− (proliferation)
CD15- (migration)
PMN-MDSC CD14- (monocyte differentiation)
CD11b+ (migration)
HLA-DR+ (proliferation)
CD15+ (migration)
CD33int (adhesion)
LOX-1+ (proliferation)
  1. Legend-CD Cluster of Differentiation; PMN-MDSC PolyMorphoNucler-Myeloid Derived Suppressor Cell; M Monocytic-Myeloid Derived Suppressor Cell; LOX-1 Lectin-like OXidized low-density lipoprotein (LDL) receptor-1