Ambient bright light treatment improved proxy-rated sleep but not sleep measured by actigraphy in nursing home patients with dementia: a placebo-controlled randomised trial

Table 4 Showing the results of the linear mixed model analyses

Variables	n	Nmb obs	Baseline to week 8				Baseline to week 16				Baseline to week 24
Variables	n	Nmb obs	Regression coefficient	Std.error	P	CI	Regression coefficient	Std.error	P	CI	Regression coefficient	Std.error	P	CI
SE^a	65	201	−0.32	3.18	.920	−6.56-5.92	2.97	3.36	.377	−3.60-9.55	−3.65	3.26	.264	−10.04-2.73
TST 24 h^b,c	65	194	−52.18	30.86	.093	−112.66-8.03	−36.11	33.95	.290	−102.64-30.43	−12.46	31.41	.692	−74.03-49.10
TST day^c	65	201	6.65	14.03	.636	−20.84-34.14	24.83	14.79	.096	−4.16-53.81	21.44	14.35	.138	-6.69-49.57
WASO^d	65	201	14.42	10.43	.169	−6.03-34.86	2.59	10.98	.814	−18.92-24.11	20.92	10.68	.052	0.01–41.85
SDI trans^e	66	213	−0.04	.02	.094	−0.09-0.01	−0.06	.03	.020	−0.11--0.01	− 0.05	0.02	.028	−0.10--0.01

Note: The R package lme4 assumes an unstructured variance-covariance structure
CI confidence interval, Nmb obs Number of observations, P p-value, SDI Sleep Disorder Inventory, SE (variable) sleep efficiency, std.error standard error, trans transformed, TST total sleep time, WASO wake after sleep onset
Note: The regression coefficients reflect the change from baseline in the intervention group compared to the control group
^aEye disease included as covariate
^bDrop-out included as covariate
^cTotal Functional Assessment Staging score in the relevant week included as covariate
^dAge included as covariate
^eAverage number of psychotropic medications included as covariate

ISSN: 1471-2318