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Table 3 Effect of the intervention on the outcomes

From: Effects of an interprofessional Quality Circle-Deprescribing Module (QC-DeMo) in Swiss nursing homes: a randomised controlled trial

  Regression coefficient 95% confidence interval p-value
Primary outcomes
 % of PIM galenic units −0.014 [−0.038;+0.010] 0.240
 Number of PIM DDD/res −0.183 [−0.392;+0.025] 0.083
Secondary outcomes
 Number of DDD/res to avoid −0.035 [−0.095;+0.025] 0.252
 Number of DDD/res to reevaluate −0.237 [− 0.435;−0.040] 0.020
Safety outcomes
 Mortality rate a
  Intervention group −12.7% [−21.5%;−4.0%] 0.005
  Geriatric mission +8.7% [+0.8%;+16.6%] 0.032
  Group × mission −11.4% [−23.3%;+0.05%] 0.060
 Days in hospital (n = 51) a,b
  Intervention group +1.551 [+0.164;+2.938] 0.029
  Geriatric mission −1.381 [−2.670;−0.091] 0.036
  Group × mission +1.910 [+ 0.020;+3.799] 0.048
Number of falls (n = 46) b −0.165 [−0.754;+0.424] 0.575
Rate of physical restraints use (n = 46) −4.2% [−16.0%;+7.6%] 0.479
  1. All data are difference between intervention and control group at follow-up, estimated using linear regression models, under adjustment for outcome baseline value, canton, mission and size of the NH. n = 55, unless otherwise specified. PIM potentially inappropriate medication, DDD/res defined daily dose per average resident and per day. a: also adjusted for the interaction between group and mission, as it proved significant. b: reported per average resident and per year