Table 1 PICO statement for study inclusion
Population | Older people (mean age 65+) who live with frailty measured objectively by any reliable tool. |
|---|---|
Intervention | Studies at any setting and any language that included deprescribing medication review (including tapering/dose reduction, stopping or switching drugs). Deprescribing as the only intervention or part of medication review where deprescribing accounts for at least 50% of changes. |
Comparator | Any, or no, comparator considered |
Outcomes | Primary outcome: safety of deprescribing Secondary outcomes: clinical outcomes, medication-related outcomes, feasibility of deprescribing, acceptability and cost-related outcomes. |