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Table 2 Adjusted association of salivary flow rate with cognitive impairment (n = 649)

From: Salivary flow rate and the risk of cognitive impairment among Korean elders: a cross-sectional study

Variables

OR (95% Confidence Interval)

p-value

Salivary flow rate

 

0.02

Normal (≥ 0.3 mL/min)

1

 

Low (< 0.3 mL/min)

1.45 (1.05–2.11)

 

Denture status

 

0.5

 Dentate

1

 

 Denture

1.13 (0.80–1.61)

 

Age (year)

1.01 (0.98–1.05)

0.4

Sex

 

0.4

 Male

1

 

 Female

0.80 (0.50–1.31)

 

Education level

 

< 0.001

 Junior school or less

1

 

 High school or higher

0.43 (0.27–0.67)

 

Smokinga

 

0.1

 No

1

 

 Yes

0.67 (0.40–1.10)

 

Drinkingb

 

0.06

 No

1

 

 Yes

0.71 (0.49–1.01)

 

Diabetesc

 

0.02

 No

1

 

 Yes

1.53 (1.07–2.20)

 

Hypertensiond

 

0.04

 No

1

 

 Yes

0.69 (0.50–0.97)

 

Obesitye

 

0.02

 No

1

 

 Yes

0.66 (0.46–0.93)

 
  1. p-values were obtained by logistic regression adjusted for denture status, age, sex, education level, smoking, drinking, diabetes, hypertension, and obesity
  2. aSmoking: “No” refers to never smoked and “Yes” refers to past and current smoker
  3. bAlcohol intake: No refers to never drunken, and “Yes” refers to past and current drinker
  4. cDiabetes was determined as “Yes” if fasting plasma glucose > 126 mg/dL or HbA1C ≥ 6.5% or history of diabetes
  5. dHypertension was determined as “Yes” if systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg or taking hypertension medication
  6. eObesity: Body mass index (kg/m2) ≥ 25