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Table 3 Predictors of the early discontinuation of antiplatelets within 6 months after ischemic stroke compared to continuers

From: Effect of antiplatelet persistence on long-term mortality and predictors of non-persistence in ischemic stroke patients 75 years and older: a nationwide cohort study

Factors

Univariate logistic regression analysis

Multivariate logistic regression analysis

Crude OR (95% CI)

p value

Adjusted ORa(95% CI)

p value

Sex

 Male

1 (reference)

 

1 (reference)

 

 Female

1.02 (0.77-1.35)

0.889

0.97 (0.73-1.29)

0.857

Age

 75-79

1 (reference)

 

1 (reference)

 

 80-84

1.46 (1.07-2.00)

0.016

1.52 (1.11-2.09)

0.009

 ≥ 85

1.70 (1.15-2.51)

0.007

1.73 (1.17-2.57)

0.007

Income

 High

1 (reference)

 

1 (reference)

 

 Middle

1.40 (0.99-1.98)

0.055

1.43 (1.00-2.03)

0.048

 Low

1.43 (1.04-1.98)

0.030

1.38 (0.95-2.02)

0.093

Residential area

 Urban

1 (reference)

 

1 (reference)

 

 Rural

1.26 (0.89-1.78)

0.191

1.23 (0.86-1.76)

0.256

Health insurance

 Medicare

1 (reference)

 

1 (reference)

 

 Medical aid

1.21 (0.76-1.92)

0.423

1.09 (0.63-1.88)

0.758

Charlson comorbidity index

 < 6

1 (reference)

 

1 (reference)

 

 ≥ 6

2.34 (1.33-4.13)

0.003

2.56 (1.43-4.55)

0.001

Number of prescribed medications

 ≥ 4

1 (reference)

 

1 (reference)

 

 < 4

1.50 (1.05-2.13)

0.024

1.54 (1.08-2.21)

0.000

  1. aAdjusted for sex, age, income, residential area, type of health insurance, Charlson comorbidity index, and number of prescribed medications