Table 1 Characteristics of AD and non-AD cohorts
From: The effect of comorbidities on survival in persons with Alzheimer’s disease: a matched cohort study
Characteristic | AD Cohort N = 70,718 | non-AD Cohort N = 70,718 | P-value |
|---|---|---|---|
Sociodemographic factors | |||
Age at beginning of follow-up, mean (SD) | 80.05 (7.1) | 80.02 (7.1) | matched |
Categorized age at beginning of follow-up | 0.429 | ||
< 80 y | 31,971 (45.21) | 32,119 (45.42) | |
≥ 80 y | 38,747 (54.79) | 38,599 (54.58) | |
Sex | matched | ||
Women | 46,116 (65.21) | 46,116 (65.21) | |
Men | 24,602 (34.79) | 24,602 (34.79) | |
Highest occupational social class | < 0.001 | ||
Managerial/ professional | 14,692 (20.78) | 14,929 (21.11) | |
Office worker | 5973 (8.45) | 5888 (8.33) | |
Farming/forestry | 13,439 (19.00) | 13,990 (19.78) | |
Sales/industry/cleaning | 30,148 (42.63) | 27,748 (39.24) | |
Unknown/did not respond | 6466 (9.14) | 8163 (11.54) | |
Comorbidities | |||
Any cardiovascular disease | 35,026 (49.53) | 34,757 (49.15) | 0.153 |
Coronary artery disease | 21,668 (30.64) | 20,006 (28.29) | < 0.001 |
Stroke | 6825 (9.65) | 5833 (8.25) | < 0.001 |
Diabetes | 13,714 (19.39) | 8081 (11.43) | < 0.001 |
Asthma/COPD | 7557 (10.69) | 7646 (10.81) | 0.445 |
History of hip fracture | 3709 (5.24) | 2561 (3.62) | < 0.001 |
Cancer treatment within 5 years of start of follow-up | 16,200 (22.91) | 12,916 (18.26) | < 0.001 |
Any mental or behavioral disorder (exc. dementia) | 41,106 (58.13) | 36,997 (52.32) | < 0.001 |
Follow-up | |||
Duration of follow-up days, mean (min.-max.) | 1787 (7–4016) | 2038 (4–4016) | < 0.001 |
Died during follow-up | 44,585 (63.05) | 26,410 (37.35) | < 0.001 |
Died during 4-y follow-up | 24,277 (34.33) | 15,685 (22.18) | < 0.001 |