Table 2 Association between delirium symptom domain and mortality in included studies
Delirium symptom domain | Study | Mortality | Ratio type | Comparison | Assessment tool used for symptom domain | Ratio (95% CI) | p-value | Adjustments |
|---|---|---|---|---|---|---|---|---|
Altered level of arousal | ||||||||
Garcez 2020 | 30-day mortality | OR | Altered vs. Normal arousal | GCS | 1.62 (1.13–2.33) | 0.009 | Age, sex, delirium, comorbidities, nutritional status, baseline cognitive impairment, polypharmacy | |
Han 2017 | 6-month mortality | HR | Decreased arousal/delirium vs. No delirium | RASS | 1.4 (0.9–2.1) | > 0.05 | Age, sex, comorbidity burden, severity of illness, dementia, functional dependence, admission status | |
Hall 2018 | 12-month mortality | OR | Altered vs Normal arousal | OSLA | 2.21 (1.01–4.86) | < 0.05 | Age, sex, comorbidity burden, severity of illness | |
Diwell 2018 | Mortality at any timepointa | HR | Altered arousal/Delirium vs. No delirium | s-CAM | 1.33 (0.98–1.79) | 0.063 | Age, sex, co-morbidity burden, pressure sores, severity of illness | |
Jackson 2018 | 12-month mortality | HR | Decreased vs. Normal arousal/delirium | OSLA | 1.09 (1.02–1.18) | 0.01 | Age | |
Inattention | ||||||||
Bellelli 2015 | In-hospital mortality | OR | No delirium | SBT | 3.26 (2.03–5.24)b | < 0.0001 | Age, sex, nursing home residence, prior hospitalisation (6-month period), co-morbidity, dementia | |
Hall 2018 | 12-month mortality | OR | Altered vs. Normal arousal | EDTB | 1.18 (0.44–3.16) | > 0.05 | Age, sex, comorbidity burden, severity of illness | |
Diwell 2018 | Mortality at any timepointa | HR | No delirium | s-CAM | 1.24 (0.92–1.67) | 0.152 | Age, sex, co-morbidity burden, pressure sores, severity of illness | |
Disorientation | ||||||||
Bellelli 2015 | In-hospital mortality | OR | No delirium | SBT | 3.85 (2.43–6.10)b | < 0.0001 | Age, sex, nursing home residence, prior hospitalisation (6-month period), co-morbidity, dementia | |
Memory deficits | ||||||||
Bellelli 2015 | In-hospital mortality | OR | No delirium | SBT | 2.92 (1.33–6.39)b | 0.005 | Age, sex, nursing home residence, prior hospitalisation (6-month period), co-morbidity, dementia | |
Disorganised thought | ||||||||
Diwell 2018 | Mortality at any timepointa | HR | No delirium | s-CAM | 1.42 (1.05–1.92) | 0.024 | Age, sex, co-morbidity burden, pressure sores, severity of illness | |
Psychotic features (hallucinations and delusions) | ||||||||
No studies available | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | |
Visuospatial deficits | ||||||||
No studies available | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | |
Affective disturbances | ||||||||
No studies available | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | ⁃ | |