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Table 4 Most common mmedications requiring dose adjustment or precautions, defined by the CG equation

From: Medication burden and inappropriate prescription risk among elderly with advanced chronic kidney disease

Category

Medications

Patients (%)

dose modification is recommended based on ClCr

Allopurinol

167 (30)

Atenolol

34 (6.1)

Acebutolol

31 (5.6)

Lorazepama

31 (5.6)

Hydroxyzinea

27 (4.9)

Perindopril

20 (3.6)

Bromazepama

17 (3.1)

Tianeptine

15 (2.7)

dose modification based on CrCl is not recommanded but a maximum daily dose is mentionned

Ramipril

70 (12.6)

Nebivolol

56 (10.1)

Simvastatin

37 (6.7)

no specific recommendations

Bisoprolol

93 (16.7)

Clopidogrel

91 (16.4)

Fluindione

72 (12.9)

Pravastatin

53 (9.5)

Repaglinide

35 (6.1)

Candesartan

31 (5.6)

Warfarin

15 (2.7)

Clonazepam

14 (2.5)

Celiprolol

14 (2.5)

  1. CrCl Creatinine clearance
  2. aLorazepam, Hydroxyzine and Bromazepam are both Renally Inappropriate Medications (RIM) and Potentially Inappropriate-for-the-elderly Medication (PIM)