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Table 3 Risk of poor outcome at 12 months by FI quartiles

From: Comparative utility of frailty to a general prognostic score in identifying patients at risk for poor outcomes after aortic valve replacement

Population

Quartile 1 (FI < 0.23)

Quartile 2 (FI 0.23–0.31)

Quartile 3 (FI 0.32–0.40)

Quartile 4 (FI ≥ 0.41)

P-for-trend

Combined, n/N (%) 44/228 (19.3%)

2/55 (3.6%)

6/58 (10.3%)

14/56 (25.0%)

22/59 (37.3%)

 

Unadjusted OR (95% CI)

Ref

3.1 (0.6–15.8)

8.8 (1.9–41.0)

15.8 (3.5–71.1)

< 0.001

Adjusted OR (95% CI)a

Ref

2.6 (0.5–13.9)

7.2 (1.5–34.5)

13.2 (2.8–61.1)

< 0.001

SAVR, n/N (%) 5/91 (5.5%)

1/44 (2.3%)

1/23 (4.4%)

3/19 (15.8%)

0/5 (0%)

 

Unadjusted OR (95% CI)

Ref

2.0 (0.1–32.8)

8.1 (0.8–83.3)

Not estimated

0.24

Adjusted OR (95% CI)a

Ref

1.3 (0.1–26.0)

4.4 (0.4–49.5)

Not estimated

0.53

TAVR, n/N (%) 39/137 (28.5%)

1/11 (9.1%)

5/35 (14.3%)

11/37 (29.7%)

22/54 (40.7%)

 

Unadjusted OR (95% CI)

Ref

1.7 (0.2–16.0)

4.2 (0.5–37.2)

6.9 (0.8–57.6)

0.004

Adjusted OR (95% CI)a

Ref

1.6 (0.2–16.0)

3.9 (0.4–34.8)

6.6 (0.8–55.9)

0.004

  1. aNote: adjusted models include age and sex
  2. Abbreviations: CI confidence interval, FI frailty index, OR odds ratios, SAVR surgical aortic valve replacement, TAVR transcatheter aortic valve replacement