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Table 3 Risk of poor outcome at 12 months by FI quartiles

From: Comparative utility of frailty to a general prognostic score in identifying patients at risk for poor outcomes after aortic valve replacement

PopulationQuartile 1 (FI < 0.23)Quartile 2 (FI 0.23–0.31)Quartile 3 (FI 0.32–0.40)Quartile 4 (FI ≥ 0.41)P-for-trend
Combined, n/N (%) 44/228 (19.3%)2/55 (3.6%)6/58 (10.3%)14/56 (25.0%)22/59 (37.3%) 
Unadjusted OR (95% CI)Ref3.1 (0.6–15.8)8.8 (1.9–41.0)15.8 (3.5–71.1)< 0.001
Adjusted OR (95% CI)aRef2.6 (0.5–13.9)7.2 (1.5–34.5)13.2 (2.8–61.1)< 0.001
SAVR, n/N (%) 5/91 (5.5%)1/44 (2.3%)1/23 (4.4%)3/19 (15.8%)0/5 (0%) 
Unadjusted OR (95% CI)Ref2.0 (0.1–32.8)8.1 (0.8–83.3)Not estimated0.24
Adjusted OR (95% CI)aRef1.3 (0.1–26.0)4.4 (0.4–49.5)Not estimated0.53
TAVR, n/N (%) 39/137 (28.5%)1/11 (9.1%)5/35 (14.3%)11/37 (29.7%)22/54 (40.7%) 
Unadjusted OR (95% CI)Ref1.7 (0.2–16.0)4.2 (0.5–37.2)6.9 (0.8–57.6)0.004
Adjusted OR (95% CI)aRef1.6 (0.2–16.0)3.9 (0.4–34.8)6.6 (0.8–55.9)0.004
  1. aNote: adjusted models include age and sex
  2. Abbreviations: CI confidence interval, FI frailty index, OR odds ratios, SAVR surgical aortic valve replacement, TAVR transcatheter aortic valve replacement