Association of cognitive impairment and elderly mortality: differences between two cohorts ascertained 6-years apart in China

Table 3 The subgroup analyses of hazard ratios (95% CI) for all-cause mortality according to baseline MMSE score

	MMSE	2002–2008	P-interaction	2008–2014	P-interaction
Cohort			/		P = 0.254
	MMSE 18 to 23	1.28 (1.20,1.37)		1.20 (1.12,1.28)
	MMSE<18	1.48 (1.39,1.57)		1.32 (1.25,1.41)
Sex			P = 0.663		P = 0.810
Male	MMSE 18 to 23	1.26 (1.14,1.39)		1.20 (1.08,1.34)
Male	MMSE<18	1.42 (1.29,1.57)		1.23 (1.11,1.36)
Female	MMSE 18 to 23	1.31 (1.21,1.42)		1.21 (1.10,1.32)
Female	MMSE<18	1.51 (1.40,1.63)		1.40 (1.29,1.51)
Age			P < .001		P < .001
65–79	MMSE 18 to 23	1.41 (1.16,1.72)		1.63 (1.29,2.06)
65–79	MMSE<18	2.15 (1.64,2.83)		1.79 (1.33,2.41)
80–89	MMSE 18 to 23	1.27 (1.14,1.42)		1.17 (1.04,1.33)
80–89	MMSE<18	1.75 (1.56,1.97)		1.33 (1.17,1.52)
90–99	MMSE 18 to 23	1.26 (1.14,1.40)		1.16 (1.05,1.29)
90–99	MMSE<18	1.44 (1.31,1.59)		1.39 (1.27,1.53)
100+	MMSE 18 to 23	1.09 (0.97,1.24)		0.94 (0.81,1.09)
100+	MMSE<18	1.29 (1.16,1.43)		1.11 (0.99,1.24)

Note: CI confidence interval, MMSE Mini-Mental State Examination
Reference: MMSE 24 to 30
*Hazard ratio (95% CI) was calculated from cox models after adjust age, sex, marry, living alone, educational level, exercise, smoke, drink, ADL, depression, medical service and economic status

ISSN: 1471-2318