Characteristics of resting-state functional connectivity in older adults after the PICMOR intervention program: a preliminary report

Table 2 Regions showing significant group differences in functional connectivity with seed regions

Seed region	Direction	Region	MNI coordinates			Voxel	Z value
Seed region	Direction	Region	x	y	z	Voxel	Z value
Left inferior frontal gyrus (−52, 12, 0)	INT > CONT	Temporal pole	52	10	−42	284	3.91
			44	6	−40		3.78
			46	14	−38		3.71
Left inferior frontal gyrus (−44, 18, 6)	INT > CONT	Middle frontal gyrus*	50	12	36	404	4.23
			46	24	30		3.90
			54	12	18		3.81
Left middle frontal gyrus (−42, 8, 36)	INT < CONT	Posterior cingulate cortex*	−4	−44	10	545	4.23
			14	−28	4		3.89
			−4	−54	2		3.85
		Precuneus	0	−48	54	162	3.77
			4	−50	66		3.57
			6	−60	54		3.19
		Postcentral gyrus	−10	−52	74	179	4.87
			−6	−60	70		3.92

Asterisks represent the survived functional connectivity values even when a stricter height threshold was employed to correct for whole-brain multiple comparisons (FDR, p < 0.05/6)
Abbreviations: INT the intervention group, CONT the control group, MNI Montreal Neurological Institute, FDR false discovery rate

ISSN: 1471-2318