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Table 1 Characteristic of study population at baseline (T0) stratified by mobility status

From: The impact of disease-related immobilization on thigh muscle mass and strength in older hospitalized patients

 

All (n = 41)

Immobile group (n = 22; 54%)

Mobile group (n = 19; 46%)

Female

30 (73.0)

14 (64.0)

16 (84.0)

Male

11 (27.0)

8 (36.0)

3 (16.0)

Age (y)

82.4 ± 6.6

82.5 ± 6.5

82.2 ± 6.8

Height (m)

1.61 ± 0.1

1.64 ± 0.1

1.58 ± 0.1*

BMI (kg/m2)

28.4 ± 6.4

26.3 ± 4.8

30.7 ± 7.3*

Weight loss in 6 months (kg)

2.2 ± 3.1

2.6 ± 3.0

1.7 ± 3.3

CRP (mg/dl)

2.5 ± 5.5

4.1 ± 7.1

0.6 ± 1.0*

MNA-SF score, Median (IQR)

10 (8–12)

9 (7–10)

12 (11–13)***

 Normal nutritional status (n; %)

14 (34.0)

1 (4.0)

13 (68.0)

 At risk of malnutrition (n; %)

22 (54.0)

16 (73.0)

6 (32.0)

 Malnourished (n; %)

5 (12.0)

5 (23.0)

0 (0.0)

Barthel-Index on admission, Median (IQR)

55 (40–67)

40 (35–51)

70 (60–80)***

Frail Simple scale score, Median (IQR)

3 (2–3)

3 (2–3)

3 (2–3)

SARC-F scores, Median (IQR)

6 (4–7)

7 (5–8)

5 (2–6)**

CCI score, Median (IQR)

2 (1–3)

2 (1–3)

2 (1–2)

Handgrip strength (kg)

19.8 ± 8.3

20.1 ± 8.3

19.4 ± 8.5

Isometric knee extension strength (kg)

16.6 ± 6.7

16.4 ± 6.9

17.0 ± 6.8

Mid-thigh MRI cross sectional area (cm2)

 Muscle area

81.2 ± 18.2

78.7 ± 17.3

84.0 ± 19.3

 Subcutaneous fat area

89.4 ± 53.2

80.0 ± 44.4

100.3 ± 61.3

 Intermuscular fat area

18.1 ± 9.5

17.1 ± 9.0

19.2 ± 10.3

  1. CRP C-reactive protein, MNA-SF Mini Nutritional Assessment Short Form (normal nutritional status 12–14 points, at risk of malnutrition 8–11 points and malnourished 0–7 points); Frail Simple scale (not frail with score 0, pre-frail with scores of 1–2 and frail with 3–5); SARC-F scores (high risk of sarcopenia with score ≥ 4); CCI Charlson Comorbidity Index, MRI Magnetic Resonance Imaging. Values are given as mean ± SD, number (%) or median (IQR, interquartile range). There were no significant differences in gender distribution between the mobile and immobile groups (P = 0.138). *P < 0.05, **P < 0.01, ***P < 0.001, Difference between immobile and mobile patients (unpaired t test)