Table 2 Multivariable Cox proportional hazardous regression model for overall survival and cancer-specific survival
Characteristics | Hazard Ratio [95% CI] | p |
|---|---|---|
Overall Survival | ||
Urinary Diversion | ||
Ileal Conduit | 1 [Reference] | |
Uretero-cutaneostomy | 1.044 [0.867–1.257] | 0.651 |
Age | 1.067 [1.032–1.103] | < 0.001 |
Sex | ||
Female | 1 [Reference] | |
Male | 0.857 [0.521–1.411] | 0.545 |
Marital Status | ||
Married | 1 [Reference] | |
Single | 1.018 [0.828–1.251] | 0.867 |
Unknown | 1.039 [0.593–1.822] | 0.894 |
Year of Diagnosis | ||
2004 ~ 2010 | 1 [Reference] | |
2011 ~ 2016 | 0.923 [0.700–1.217] | 0.569 |
Race/Ethnicity | ||
White | 1 [Reference] | |
Black | 0.894 [0.555–1.440] | 0.644 |
Asian | 0.911 [0.574–1.445] | 0.692 |
Insurance | ||
Insured | 1 [Reference] | |
Uninsured | 1.136 [0.156–8.259] | 0.900 |
Unknown | 1.005 [0.814–1.241] | 0.963 |
Tumor Grade | ||
Urothelial Carcinoma, Low Grade | 1 [Reference] | |
Urothelial Carcinoma, High Grade | 1.228 [0.777–1.941] | 0.379 |
Urothelial Carcinoma, NOS | 1.024 [0.461–2.276] | 0.953 |
non-Urothelial Carcinoma | 1.533 [0.891–2.638] | 0.123 |
Tumor Stage | ||
Localized | 1 [Reference] | |
Regional | 1.730 [1.375–2.176] | < 0.001 |
Distant | 5.332 [3.610–7.875] | < 0.001 |
Unknown | 3.017 [0.679–13.411] | 0.147 |
Tumor Size | ||
Less than 3 cm | 1 [Reference] | |
Greater than 3 cm | 1.185 [0.930–1.510] | 0.170 |
Unknown | 1.253 [0.969–1.619] | 0.085 |
Node Density | ||
None | 1 [Reference] | |
≤ 0.2 | 0.941 [0.658–1.344] | 0.737 |
>0.2 | 1.410 [1.047–1.898] | 0.024 |
Unknown | 1.487 [1.167–1.895] | 0.001 |
Cancer-Specific Survival | ||
Urinary Diversion | ||
Ileal Conduit | 1 [Reference] | |
Uretero-cutaneostomy | 1.012 [0.748–1.368] | 0.940 |
Age | 0.983 [0.928–1.041] | 0.561 |
Sex | ||
Female | 1 [Reference] | |
Male | 0.795 [0.374–1.690] | 0.551 |
Marital Status | ||
Married | 1 [Reference] | |
Single | 1.297 [0.934–1.801] | 0.120 |
Unknown | 1.308 [0.558–3.065] | 0.537 |
Year of Diagnosis | ||
2004 ~ 2010 | 1 [Reference] | |
2011 ~ 2016 | 1.242 [0.828–1.863] | 0.294 |
Race/Ethnicity | ||
White | 1 [Reference] | |
Black | 0.768 [0.336–1.756] | 0.532 |
Asian | 0.795 [0.367–1.724] | 0.561 |
Insurance | ||
Insured | 1 [Reference] | |
Uninsured | 2.707 [0.354–20.679] | 0.337 |
Unknown | 1.118 [0.789–1.583] | 0.532 |
Tumor Grade | ||
Urothelial Carcinoma, Low Grade | 1 [Reference] | |
Urothelial Carcinoma, High Grade | 0.934 [0.482–1.807] | 0.838 |
Urothelial Carcinoma, NOS | 0.688 [0.185–2.556] | 0.577 |
non-Urothelial Carcinoma | 1.241 [0.547–2.813] | 0.606 |
Tumor Stage | ||
Localized | 1 [Reference] | |
Regional | 2.476 [1.651–3.713] | < 0.001 |
Distant | 4.035 [2.046–7.959] | < 0.001 |
Unknown | 3.093 [0.354–27.006] | 0.307 |
Tumor Size | ||
Less than 3 cm | 1 [Reference] | |
Greater than 3 cm | 1.596 [1.057–2.412] | 0.026 |
Unknown | 1.378 [0.872–2.176] | 0.17 |
Node Density | ||
None | 1 [Reference] | |
≤ 0.2 | 1.062 [0.590–1.914] | 0.840 |
>0.2 | 2.501 [1.645–3.804] | < 0.001 |
Unknown | 1.995 [1.340–2.969] | 0.001 |