Skip to main content

Table 3 Risk factors for the development of early post-transplant infection in older recipients

From: Epidemiology, risk factors, and clinical impact of early post-transplant infection in older kidney transplant recipients: the Korean organ transplantation registry study

≥ 60 year-old

Univariate

Multivariate

HR (95% CI)

p

HR (95% CI)

p

Sex, female

1.548 (1.119–2.142)

0.008

1.398 (1.199–1.631)

<  0.001

BMI (kg/m2)

0.991 (0.939–1.046)

0.741

  

Cause of ESRD

 Diabetes mellitus

1

   

 Hypertension

0.898 (0.554–1.454)

0.661

  

 Glomerulonephritis

1.192 (0.767–1.854)

0.436

  

 ADPKD

0.781 (0.334–1.823)

0.568

  

 Others

1.135 (0.452–2.850)

0.787

  

 Unknown

1.226 (0.778–1.932)

0.379

  

Duration of dialysis (month)

1.003 (1.001–1.005)

0.004

1.001 (1.000–1.002)

0.156

Diabetes mellitus

0.880 (0.635–1.219)

0.441

  

Hypertension

0.663 (0.375–1.172)

0.157

  

Cardiovascular disease

0.931 (0.627–1.384)

0.725

  

Creatinine, baseline (mg/dL)

0.988 (0.935–1.045)

0.680

  

Creatinine, discharge (mg/dL)

1.153 (0.945–1.408)

0.161

  

Re-transplantation

0.994 (0.520–1.901)

0.986

  

Deceased donor

1.495 (1.076–2.077)

0.017

1.364 (1.137–1.637)

0.001

Donor age (year)

1.022 (1.009–1.034)

0.001

1.010 (1.004–1.016)

0.001

Donor sex, female

1.204 (0.864–1.677)

0.273

  

Desensitization

1.257 (0.849–1.859)

0.253

  

ABO incompatibility

1.050 (0.662–1.667)

0.836

  

Presence of DSA

1.324 (0.749–2.340)

0.334

  

Length of hospitalization after KT (day)

1.016 (1.008–1.025)

<  0.001

1.010 (1.006–1.014)

<  0.001

Induction immunosuppression

No use

1

 

1

 

 Basiliximab

1.513 (0.373–6.134)

0.562

2.051 (0.916–4.593)

0.081

 ATG

2.022 (0.489–8.357)

0.331

2.131 (0.941–4.827)

0.070

 Basiliximab + ATG

5.087 (0.987–26.223)

0.052

2.138 (0.851–5.370)

0.106

Calcineurin inhibitors

 No use

1

   

 Tacrolimus

3.285 (0.460–23.478)

0.236

  

 Cyclosporine

0.495 (0.031–7.913)

0.619

  

Steroid

0.974 (0.361–2.631)

0.958

  

Acute rejection

3.377 (2.399–4.754)

 

2.907 (2.471–3.419)

<  0.001

  1. BMI body mass index, ESRD end stage renal disease, ADPKD autosomal dominant polycystic kidney disease, DSA donor specific antibody, KT kidney transplantation, ATG anti-thymocyte globulin