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Table 4 Association between PLR, NLR, LMR, CRP (per 1-SD) and sarcopenia according to Logistic Regression Models adjusted for potential confounders

From: Inflammatory indexes are not associated with sarcopenia in Chinese community-dwelling older people: a cross-sectional study

 

Unadjusted

Model 1

Model 2

Model 3

AWGS-defined sarcopenia

 PLR (per 1-SD)

1.19 (0.92–1.53)

1.16 (0.88–1.53)

1.19 (0.91–1.58)

1.09 (0.82–1.45)

 NLR (per 1-SD)

0.97 (0.73–1.28)

1.04 (0.77–1.40)

1.04 (0.77–1.40)

0.96 (0.71–1.30)

 LMR (per 1-SD)

0.99 (0.75–1.30)

0.97 (0.72–1.32)

0.96 (0.70–1.31)

1.01 (0.74–1.38)

 CRP (per 1-SD)

1.11 (0.86–1.44)

1.07 (0.81–1.42)

1.06 (0.80–1.41)

1.14 (0.85–1.54)

AWGS 2019-defined sarcopenia

 PLR (per 1-SD)

1.10 (0.90–1.35)

1.09 (0.89–1.35)

1.10 (0.89–1.36)

0.86 (0.67–1.10)

 NLR (per 1-SD)

1.09 (0.89–1.33)

1.11 (0.90–1.37)

1.10 (0.89–1.36)

0.91 (0.71–1.17)

 LMR (per 1-SD)

0.97 (0.79–1.19)

1.00 (0.81–1.25)

1.01 (0.82–1.26)

1.15 (0.89–1.47)

 CRP (per 1-SD)

0.91 (0.75–1.12)

0.89 (0.71–1.10)

0.89 (0.71–1.10)

1.10 (0.86–1.41)

EWGSOP-defined sarcopenia

 PLR (per 1-SD)

1.28 (0.97–1.69)

1.27 (0.95–1.70)

1.27 (0.95–1.70)

1.01 (0.74–1.38)

 NLR (per 1-SD)

1.28 (0.97–1.68)

1.36 (1.02–1.81)

1.37 (1.02–1.82)

1.14 (0.83–1.56)

 LMR (per 1-SD)

0.78 (0.56–1.09)

0.77 (0.54–1.10)

0.75 (0.53–1.08)

0.86 (0.58–1.27)

 CRP (per 1-SD)

0.81 (0.56–1.18)

0.17 (0.75–1.13)

0.74 (0.49–1.11)

0.93 (0.61–1.43)

EWGSOP2-defined sarcopenia

 PLR (per 1-SD)

1.25 (0.92–1.68)

1.24 (0.91–1.69)

1.23 (0.89–1.69)

0.99 (0.71–1.38)

 NLR (per 1-SD)

1.23 (0.91–1.65)

1.28 (0.94–1.75)

1.30 (0.95–1.77)

1.11 (0.79–1.54)

 LMR (per 1-SD)

1.02 (0.73–1.42)

1.07 (0.75–1.53)

1.05 (0.73–1.51)

1.26 (0.84–1.87)

 CRP (per 1-SD)

1.00 (0.72–1.40)

0.97 (0.68–1.38)

0.95 (0.66–1.36)

1.17 (0.79–1.74)

IWGS-defined sarcopenia

 PLR (per 1-SD)

1.15 (0.92–1.43)

1.14 (0.90–1.44)

1.13 (0.89–1.44)

1.04 (0.81–1.33)

 NLR (per 1-SD)

0.96 (0.76–1.22)

0.99 (0.77–1.27)

0.98 (0.77–1.26)

0.92 (0.71–1.18)

 LMR (per 1-SD)

0.98 (0.78–1.24)

1.02 (0.79–1.32)

1.02 (0.79–1.32)

1.07 (0.83–1.39)

 CRP (per 1-SD)

0.96 (0.76–1.22)

0.92 (0.78–1.19)

0.92 (0.71–1.19)

0.98 (0.75–1.28)

FNIH-defined sarcopenia

 PLR (per 1-SD)

0.90 (0.67–1.21)

0.85 (0.62–1.17)

0.85 (0.61–1.17)

0.88 (0.63–1.23)

 NLR (per 1-SD)

0.81 (0.59–1.10)

0.82 (0.59–1.15)

0.83 (0.59–1.16)

0.85 (0.60–1.20)

 LMR (per 1-SD)

1.27 (0.97–1.66)

1.42 (1.04–1.93)

1.40 (1.03–1.91)

1.39 (1.01–1.90)

 CRP (per 1-SD)

1.09 (0.84–1.42)

1.05 (0.78–1.41)

1.04 (0.77–1.40)

1.02 (0.74–1.40)

  1. Notes: Data are presented as odds ratios (95% confidential intervals). PLR, NLR, MLR were treated as continuous variables (per 1-SD)
  2. Model 1: adjusted for age and gender. Model 2: adjusted for age, gender, coronary heart disease, and cognitive impairment. Model 3: adjusted for age, gender, coronary heart disease, cognitive impairment, albumin, HDL-C, and BMI
  3. Abbreviations: AWGS Asia Working Group for Sarcopenia, AWGS 2019 the updated version of AWGS, CRP C-reactive protein, EWGSOP European Working Group on Sarcopenia in Older People, EWGSOP2 the updated version of EWGSOP, FNIH the Foundation for the National Institutes of Health, IWGS International Working Group on Sarcopenia, LMR lymphocyte-to-monocyte ratio, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, SD standard deviation