Table 3 Factors associated with one-year mortality in Cox Proportional Hazards regression (N = 314)
Variables | Univariate model | Multivariable model | ||
|---|---|---|---|---|
HR [95% CI] | p-value | HR [95% CI] | p-value | |
Socio-demographic characteristics | ||||
Category of ages | ||||
Age < 80 years | 1.00 | |||
Age 80–84 years | 0.89 [0.53; 1.50] | 0.660 | ||
Age 85–89 years | 1.04 [0.62; 1.76] | 0.879 | ||
Age ≥ 90 years | 1.41 [0.80; 2.49] | 0.234 | ||
Sex (male vs. female) | 1.26 [0.88; 1.80] | 0.207 | ||
Health status, comorbidities and geriatric characteristics | ||||
Health status (poor vs. intermediate) | 1.80 [1.18; 2.74] | 0.007 | 1.59 [1.04; 2.43] | 0.033 |
Ischaemic heart disease | 1.44 [1.01; 2.06] | 0.045 | 1.39 [0.97; 1.98] | 0.074 |
Nursing home residency | 1.67 [1.13; 2.48] | 0.010 | ||
Malnutrition | 1.65 [1.15; 2.38] | 0.007 | 1.67 [1.16; 2.42] | 0.006 |
Recent falls | 0.64 [0.45; 0.92] | 0.015 | 0.63 [0.44; 0.91] | 0.013 |
Functional impairmenta | 1.65 [1.11; 2.46] | 0.014 | ||
Polypharmacy | ||||
Absent (0–4 drugs/day) | 1.00 | |||
Moderate (5–9 drugs/day) | 2.08 [0.83; 5.19] | 0.117 | ||
Major (≥ 10 drugs/day) | 2.41 [0.97; 6.01] | 0.059 | ||
GLT characteristics | ||||
Appropriateness | ||||
Present | 1.00 | 1.00 | ||
Undertreatment | 1.22 [0.65; 2.27] | 0.534 | 1.22 [0.65; 2.28] | 0.542 |
Overtreatment | 1.80 [1.12; 2.89] | 0.015 | 1.73 [1.08; 2.79] | 0.023 |
Category of HbA1c | ||||
HbA1c < 6.5% | 1.82 [1.02; 3.22] | 0.042 | ||
HbA1c 6.5–7.4% | 1.05 [0.58; 1.92] | 0.866 | ||
HbA1c 7.5–8.4% | 1.00 | |||
HbA1c ≥ 8.5% | 1.16 [0.58; 2.33] | 0.672 | ||
Use of hypoglycaemic agents | 1.71 [1.03; 2.86] | 0.040 | ||
Use of metformin | 0.62 [0.42; 0.91] | 0.015 | ||