Table 3 Top 20 medications that contributed to the anticholinergic burden score in dementia patients with high exposure prior to 2–10 years of dementia according to the scales

chlorpheniramine^{a, b}

1,297

(98.0)

17

3

5.8

3

5.2

tramadol^a

1,262

(95.3)

9.2

2

2.3

0

0

cimetidine^{a, b}

1,260

(95.2)

46.7

2

11.6

1

4.0

diazepam^{a, b}

1,198

(90.5))

34.8

1

4.2

1

3.4

ranitidine^{a, b}

1,150

(86.9)

28.6

1

3.1

1

3.0

hydrochlorothiazide^b

974

(73.6)

80.2

0

0

1

10.1

alprazolam^{a, b}

921

(69.6)

32.5

1

4.1

1

3.2

dimenhydrinate^{a, b}

869

(65.6)

33.3

3

11.3

3

11.7

amitriptyline^{a, b}

727

(54.9)

10.9

3

3.8

3

3.4

theophylline^{a, b}

664

(50.2)

13.8

1

1.5

1

1.5

furosemide^{a, b}

606

(45.8)

39.5

1

4.3

1

5.0

atenolol^b

549

(41.5)

33

0

0

1

4.3

lorazepam^a

515

(38.9)

11.9

1

1.5

0

0

nifedipine^b

459

(34.7)

38

0

0

1

5.2

triazolam^a

454

(34.3)

15.8

1

2.1

0

0

octylonium bromide^a

451

(34.1)

4.5

3

1.8

0

0

tolterodine^{a, b}

355

(26.8)

7.9

3

2.7

3

2.8

propiverine^{a, b}

342

(25.8)

6.3

3

2.2

3

2.2

isosorbide^b

290

(21.9)

40.2

0

0

1

5.4

doxazosin^b

263

(19.9)

18.1

0

0

1

2.4

digoxin^b

215

(16.2)

13.3

1

1.2

1

1.7

paroxetine^{a, b}

209

(15.8)

9.3

2

2.1

3

3.5

quinupramine^a

188

(14.2)

5.1

3

2.2

0

0

solifenacin^{a, b}

174

(13.1)

6.1

3

2.1

3

2.3

levodopa and decarboxylase inhibitor^a

166

(12.5)

12.6

1

1.8

0

0

beztropine^b

77

(5.8)

3.6

3

1.4

3

1.3

amantadine^a

76

(5.7)

6.3

2

1.8

2

1.1