Table 4 Factors associated with PIMs and DDIs in elderly (> 70 years) multidose users in Norway in 2018
From: Potentially inappropriate prescribing to older patients receiving multidose drug dispensing
Study population | Potentially inappropriate medications (PIM) | Drug-drug interactions (DDI) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type Ba | Type Ca | ||||||||||||
n | n | (%) | OR | (95% CI) | n | (%) | OR | (95% CI) | n | (%) | n | (%) | |
Age 70–79 | 11,435 | 4072 | (35.6) | 1 | (ref) | 7227 | (63.2) | 1 | (ref) | 7171 | (62.7) | 493 | (4.3) |
Age 80–89 | 21,633 | 5449 | (25.2) | 0.61 | (0.57–0.64) | 13,000 | (60.1) | 0.90 | (0.85–0.95) | 12,935 | (59.8) | 543 | (2.5) |
Age 90+ | 12,525 | 2793 | (22.3) | 0.55 | (0.52–0.59) | 6785 | (54.2) | 0.76 | (0.72–0.81) | 6754 | (53.9) | 226 | (1.8) |
No. of drugs | 45,593 | NA | 1.15b | (1.15–1-16) | NA | 1.30b | (1.28–1.30) | NA | NA | ||||
Male | 15,503 | 8814 | (22.6) | 1 | (ref) | 8354 | (53.9) | 1 | (ref) | 8294 | (53.5) | 420 | (2.7) |
Female | 30,090 | 3505 | (29.3) | 1.50 | (1.43–1.58) | 18,658 | (62.0) | 1.43 | (1.37–1.50) | 18,566 | (61.7) | 842 | (2.8) |