Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

Table 5 Multiple regression models with carer-related QoL measures as dependent variables. The model fit is reported for each model, and the contribution of disease severity (sMMSE) reported (ΔR² and p-value). Individual variables beta coefficients (including 95% CIs) are also reported

		Coefficients					Model change		Model
Model	Independent variables	β	B	B Lower 95% CI	B Upper 95% CI	p	ΔR²	p	Adjusted R²	F	p
EQ-5D carer (n = 213)							0.01	0.19	0.12	5.83	< 0.001
	Carer gender: Male	0.08	0.04	−0.02	0.10	0.19
	Residential setting: Care home	−0.09	− 0.05	−0.13	0.03	0.19
	Carer age	−0.13	0.00	−0.01	0.00	0.10
	Relationship: Spouse	−0.04	−0.02	−0.10	0.07	0.66
	NPI	0.08	0.00	0.00	0.00	0.24
	ZCBI	−0.28	−0.01	−0.01	−0.00	0.00
	DEMQOL-Proxy	0.14	0.00	0.00	0.01	0.03	`
	sMMSE	−0.09	−0.00	−0.01	0.00	0.19
SF-12 Physical Health (n = 273)							0.003	0.37	0.05	2.80	0.01
	Carer gender: Male	0.02	0.54	−2.47	3.54	0.72
	Residential setting: Care home	−0.12	−3.44	−7.64	0.75	0.11
	Carer age	−0.17	−0.18	− 0.35	−0.01	0.04
	Relationship: Spouse	−0.03	−0.79	−5.09	3.52	0.72
	NPI	0.03	0.02	−0.10	0.14	0.70
	ZCBI	−0.16	−0.13	−0.23	− 0.02	0.02
	DEMQOL-Proxy	0.09	0.08	−0.04	0.19	0.18
	sMMSE	−0.0	−0.08	−0.27	0.10	0.37
SF-12 Mental Health (n = 273)							< 0.001	0.97	0.43	26.56	< 0.001
	Carer gender: Male	0.07	1.57	−0.50	3.64	0.14
	Residential setting: Care home	−0.09	−2.46	−5.35	0.43	0.10
	Carer age	0.16	0.14	0.02	0.26	0.02
	Relationship: Spouse	−0.05	−1.03	−3.99	1.94	0.50
	NPI	−0.07	−0.05	−0.13	0.03	0.22
	ZCBI	−0.57	−0.39	−0.46	− 0.32	0.00
	DEMQOL-Proxy	0.13	0.10	0.02	0.18	0.02
	sMMSE	0.00	0.00	−0.13	0.13	0.97

ISSN: 1471-2318