Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

Table 4 Multiple regression models with person with dementia QoL outcomes as dependent variables. The model fit is reported for each model, and the contribution of disease severity (sMMSE) reported (ΔR² and p-value). Individual variables beta coefficients (including 95% CIs) are also reported

		Coefficients					Model change		Model
Model	Independent Variables	β	B	B Lower 95% CI	B Upper 95% CI	p	ΔR²	p	Adjusted R²	F	p
DEMQOL (n = 177)							0.02	0.06	0.04	2.19	0.05
	Gender: Male	−0.11	−2.97	−6.92	0.98	0.14
	Residential setting: Care home	−0.13	−5.26	−11.73	1.22	0.11
	Age	0.15	0.24	−0.01	0.49	0.06
	NPI	− 0.05	−0.05	−0.19	0.09	0.49
	Carer EQ-5D	0.07	3.51	−3.81	10.84	0.35
	sMMSE	−0.15	−0.37	−0.76	0.01	0.06
EQ-5D (self) (n = 185)							0.001	0.63	0.00	0.99	0.43
	Gender: Male	−0.03	− 0.01	− 0.08	0.06	0.75
	Residential setting: Care home	−0.01	0.00	−0.12	0.11	0.95
	Age	0.04	0.00	0.00	0.01	0.60
	NPI	−0.13	0.00	0.00	0.00	0.09
	Carer EQ-5D	0.10	0.09	−0.05	0.22	0.21
	sMMSE	−0.04	0.00	−0.01	0.00	0.63
CASP-19 (self) (n = 155)							< 0.001	0.89	0.03	1.63	0.14
	Gender: Male	−0.10	−1.81	−4.91	1.29	0.25
	Residential setting: Care home	−0.12	−3.98	−9.73	1.77	0.17
	Age	0.21	0.25	0.05	0.45	0.02
	NPI	−0.10	−0.07	−0.20	0.06	0.27
	Carer EQ-5D	0.02	0.61	−5.26	6.47	0.84
	sMMSE	0.01	0.02	−0.29	0.34	0.89
DEMQOL-Proxy (n = 284)							0.06	< 0.001	0.22	14.14	< 0.001
	Gender: Male	0.07	2.01	−0.96	4.98	0.18
	Residential setting: Care home	−0.01	−0.39	−4.52	3.75	0.85
	Age	0.00	0.01	−0.17	0.19	0.95
	NPI	−0.43	−0.39	−0.49	− 0.29	0.00
	Carer EQ-5D	0.14	8.11	2.09	14.13	0.01
	sMMSE	−0.29	−0.44	−0.62	− 0.26	0.00
EQ-5D (proxy) (n = 276)							0.04	< 0.001	0.25	16.36	< 0.001
	Gender: Male	0.13	0.08	0.01	0.15	0.02
	Residential setting: Care home	−0.16	−0.13	−0.23	−0.03	0.01
	Age	−0.13	− 0.01	−0.01	0.00	0.02
	NPI	−0.26	−0.01	−0.01	0.00	0.00
	Carer EQ-5D	0.08	0.10	−0.04	0.24	0.15
	sMMSE	0.23	0.01	0.00	0.01	0.00

ISSN: 1471-2318