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Table 4 Multiple regression models with person with dementia QoL outcomes as dependent variables. The model fit is reported for each model, and the contribution of disease severity (sMMSE) reported (ΔR2 and p-value). Individual variables beta coefficients (including 95% CIs) are also reported

From: Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

   Coefficients Model change Model
Model Independent Variables β B B Lower 95% CI B Upper 95% CI p ΔR2 p Adjusted R2 F p
DEMQOL
(n = 177)
       0.02 0.06 0.04 2.19 0.05
Gender: Male −0.11 −2.97 −6.92 0.98 0.14      
Residential setting: Care home −0.13 −5.26 −11.73 1.22 0.11      
Age 0.15 0.24 −0.01 0.49 0.06      
NPI − 0.05 −0.05 −0.19 0.09 0.49      
Carer EQ-5D 0.07 3.51 −3.81 10.84 0.35      
sMMSE −0.15 −0.37 −0.76 0.01 0.06      
EQ-5D (self) (n = 185)        0.001 0.63 0.00 0.99 0.43
Gender: Male −0.03 − 0.01 − 0.08 0.06 0.75      
Residential setting: Care home −0.01 0.00 −0.12 0.11 0.95      
Age 0.04 0.00 0.00 0.01 0.60      
NPI −0.13 0.00 0.00 0.00 0.09      
Carer EQ-5D 0.10 0.09 −0.05 0.22 0.21      
sMMSE −0.04 0.00 −0.01 0.00 0.63      
CASP-19 (self) (n = 155)        < 0.001 0.89 0.03 1.63 0.14
Gender: Male −0.10 −1.81 −4.91 1.29 0.25      
Residential setting: Care home −0.12 −3.98 −9.73 1.77 0.17      
Age 0.21 0.25 0.05 0.45 0.02      
NPI −0.10 −0.07 −0.20 0.06 0.27      
Carer EQ-5D 0.02 0.61 −5.26 6.47 0.84      
sMMSE 0.01 0.02 −0.29 0.34 0.89      
DEMQOL-Proxy (n = 284)        0.06 < 0.001 0.22 14.14 < 0.001
Gender: Male 0.07 2.01 −0.96 4.98 0.18      
Residential setting: Care home −0.01 −0.39 −4.52 3.75 0.85      
Age 0.00 0.01 −0.17 0.19 0.95      
NPI −0.43 −0.39 −0.49 − 0.29 0.00      
Carer EQ-5D 0.14 8.11 2.09 14.13 0.01      
sMMSE −0.29 −0.44 −0.62 − 0.26 0.00      
EQ-5D (proxy) (n = 276)        0.04 < 0.001 0.25 16.36 < 0.001
Gender: Male 0.13 0.08 0.01 0.15 0.02      
Residential setting: Care home −0.16 −0.13 −0.23 −0.03 0.01      
Age −0.13 − 0.01 −0.01 0.00 0.02      
NPI −0.26 −0.01 −0.01 0.00 0.00      
Carer EQ-5D 0.08 0.10 −0.04 0.24 0.15      
sMMSE 0.23 0.01 0.00 0.01 0.00