Table 3 Analysis of The Relationship Between Baseline Slow Gait Speed and Cognition at 18 Months (ADAS-Cog) in Mild to Moderate AD. Under unadjusted or adjusted models, there was no association between baseline slow gait speed and cognition at 18 months (dependent variable). ADAS-Cog = Alzheimer Disease Assessment Scale – Cognitive Subsection
Predictor | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
β-Coef (95% CI) | P | β-Coef (95% CI) | P | βCoef (95% CI) | P | |
Baseline Slow Gait Speed | −1.49 (−4.61, 1.63) | 0.35 | −0.63 (−3.69, 2.42) | 0.69 | − 0.80 (−3.86, 2.25) | 0.606 |
Baseline ADAS-Cog | 0.22 (0.13, 0.31) | < 0.001* | 0.22 (0.13, 0.32) | < 0.001* | ||
Age | −0.21 (−0.32, − 0.10) | < 0.001* | − 0.22 (− 0.34, − 0.10) | < 0.001* | ||
Gender (Female) | 0.94 (−2.80, 0.92) | 0.321 | 0.97 (−2.83, 0.90) | 0.310 | ||
Study Arm | −0.73 (− 2.49, 1.02) | 0.414 | − 0.70 (− 2.46, 1.06) | 0.437 | ||
Body Mass Index | −0.25 (− 0.46 - -0.04) | 0.018* | − 0.27 (− 0.48 - -0.06) | 0.011* | ||
Education (Years) | 0.13 (−0.11–0.37) | 0.291 | 0.14 (− 0.10–0.38) | 0.244 | ||
Diagnosis Duration | − 0.67 (−1.22 – − 0.12) | 0.017 | −0.68 (− 1.22 – − 0.12) | 0.015 | ||
Total Medications | 0.17 (−0.18–0.52) | 0.345 | ||||
Total Comorbidities | 0.08 (−0.33–0.49) | 0.697 |