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Table 2 Developing of a prediction score for hospitalisation-associated functional decline

From: Predicting hospitalisation-associated functional decline in older patients admitted to a cardiac care unit with cardiovascular disease: a prospective cohort study

PredictorsEstimation of main effectsPrediction model a
Unadjusted OR (95% CI)Adjusted OR (95% CI)Coefficients (95% CI)Shrinked coefficientsbScore chartc
Mobility impairment3.75 (1.91–7.39)2.81 (1.37–5.77)1.03 (0.31–1.75)0.88 (0.26–1.49)9
Cognitive impairment2.97 (1.57–5.62)2.32 (1.16–4.62)0.84 (0.15–1.53)0.71 (0.13–1.30)7
Loss of appetite2.69 (1.44–5.01)2.14 (1.08–4.22)0.76 (0.08–1.44)0.64 (0.07–1.22)6
Depressive symptoms2.17 (1.10–4.27)1.70 (0.80–3.59)0.53 (− 0.22–1.28)0.45 (−0.19–1.09)5
Use of restraints2.58 (1.30–5.10)1.76 (0.84–3.70)0.57 (− 0.18–1.31)0.49 (−0.15–1.11)5
  1. Abbeviations: OR Odds Ratio, CI Confidence Interval;
  2. a Model evaluation: Discrimination: C-index = 0.76, 95% CI (0.68–0.83); Discrimination after internal validation: C-index = 0.73, 95% CI (0.65–0.80); Calibration: Hosmer-Lemeshow goodness of fit Chi2 = 8.07, p = 0.362; Assumptions: mean VIF = 1.09, VIF < 10 and tolerance > 0.1 was observed for all variables;
  3. b Coefficients were shrinked using a uniform shrinkage factor ((34.32–5)/ 34.32) = 0.85;
  4. c Score chart was developed by multiplying the shrinked coefficients with 10 and rounding the score;
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