Table 2 General characteristics in groups of eGFR< 60 and ≥ 60 mL/min/1.73m2
Variables | Total (n = 651) | eGFR< 60 (n = 174) | eGFR≥60 (n = 477) | p-value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Age, yr | 71.6 | ± | 7.5 | 75.3 | ± | 7.8 | 70.1 | ± | 6.8 | < 0.001 |
Body mass index, kg/m2 | 24.0 | ± | 3.4 | 23.7 | ± | 3.5 | 24.1 | ± | 3.4 | 0.247 |
Body surface area | 1.3 | ± | 0.3 | 1.2 | ± | 0.3 | 1.3 | ± | 0.3 | < 0.001 |
eGFR, mL/min/1.73m2 | 67.7 | [59.5, 76.2] | 53.0 | [45.4, 57.0] | 71.4 | [66.2, 78.0] | < 0.001 | |||
BUN, mg/dL | 15.8 | [13.1, 19.1] | 18.1 | [15.4, 23.3] | 15.0 | [12.6, 17.8] | < 0.001 | |||
Creatinine, mg/dL | 0.95 | [0.85, 1.09] | 1.17 | [1.00, 1.34] | 0.90 | [0.83, 1.01] | < 0.001 | |||
ADMA, μmol/L | 0.674 | ± | 0.111 | 0.691 | ± | 0.112 | 0.667 | ± | 0.11 | 0.013 |
ADMA elevation * | 182 | (28.0) | 57 | (31.3) | 125 | (26.7) | 0.237 | |||
Systolic BP, mmHg | 134.2 | ± | 20.1 | 137.3 | ± | 21.6 | 133 | ± | 19.4 | 0.014 |
Diastolic BP, mmHg | 72 | ± | 10.1 | 71.1 | ± | 10.5 | 72.3 | ± | 10 | 0.172 |
Pulse pressure, bpm | 62.2 | ± | 16.9 | 67.2 | ± | 18.1 | 61.8 | ± | 14.2 | 0.003 |
Fasting glucose, mg/dL | 90 | [83, 101] | 91 | [84, 107] | 89 | [83, 99] | 0.001 | |||
Fasting insulin, uIU/mL | 7.6 | [5.9, 10.3] | 8.4 | [6.2, 13.2] | 7.4 | [5.8, 9.9] | 0.002 | |||
Total cholesterol, mg/dL | 181.9 | ± | 36 | 175.3 | ± | 38.7 | 184.4 | ± | 34.7 | 0.003 |
HDL cholesterol, mg/dL | 50.9 | ± | 12.7 | 48.6 | ± | 12.5 | 51.8 | ± | 12.7 | 0.004 |
Triglycerides, mg/dL | 136 | [102, 188] | 149 | [109, 193] | 129 | [100, 185] | 0.844 | |||
Diabetes, % | 150 | (23.0) | 55 | (30.2) | 95 | (20.3) | 0.008 | |||
Hypertension, % | 420 | (64.5) | 139 | (76.4) | 281 | (59.9) | < 0.001 | |||
Hyperlipidemia, % | 181 | (27.8) | 57 | (31.3) | 124 | (26.4) | 0.216 | |||
Smoking | ||||||||||
Non-smoker | 456 | (70.0) | 131 | (72.0) | 325 | (69.3) | 0.792 | |||
Past smoker | 117 | (18.0) | 31 | (17.0) | 86 | (18.3) | ||||
Current smoker | 78 | (12.0) | 20 | (11.0) | 58 | (12.4) | ||||
Drinking | ||||||||||
Non-drinker | 512 | (78.7) | 157 | (86.3) | 355 | (75.7) | 0.002 | |||
Current drinker | 139 | (21.3) | 25 | (13.7) | 114 | (24.3) | ||||