Table 1 Characteristics of patients with diagnosis of sepsis in relation to age (2009–2016). Data reported as number of cases and percent and mean and [standard deviation]
From: Old subjects with sepsis in the emergency department: trend analysis of case fatality rate
Characteristics | All Cases | <80 years | ≥80 years | OR (95%CI) or P value |
|---|---|---|---|---|
Age group | 2492 | 1173 (47.1) | 1319 (52.9) | 1.11 (1.03–1.19) |
Sex (male %) | 1355 (54.4) | 672 (57.3) | 683 (51.8)* | 0.80 (0.68–0.94) |
Age (years, mean [SD]) | 77.9 [14.6] | 66.5 [12.4] | 88.1 [6.8]* | < 0.001 |
Comorbidities | ||||
Diabetes | 727 (29.2) | 300 (25.6) | 427 (32.4)* | 1.39 (1.17 - 1.66) |
COPD | 1142 (45.8) | 474 (40.4) | 668 (50.6)* | 1.51 (1.29–1.77) |
CKD | 837 (33.6) | 366 (31.2) | 471 (35.7)* | 1.22 (1.04–1.45) |
AHF | 885 (35.5) | 358 (30.5) | 538 (40.8)* | 1.56 (1.33–1.85) |
Dementia | 750 (30.1) | 213 (18.2) | 537 (40.7)* | 3.19 (2.66–3.82) |
Cancer | 1046 (42.0) | 525 (44.8) | 521 (39.5)* | 0.81 (0.69–0.94) |
HIV infection | 24 (1.0) | 2 (0.2) | 22 (1.9)* | 0.79 (0.19–0.34) |
Vial Signs at ED arrival | ||||
Body temperature C | 37.6 (0.8) | 37.7 (0.8) | 37.5 (0.7)* | <0.001 |
Heart rate (beats/min) | 97.2 (19.6) | 98.2 (19.6) | 96.3 (19.6)* | 0.016 |
Systolic blood pressure (mmHg) | 117.5 (24.0) | 117.2 (23.0) | 117.9 (24.8) | 0.464 |
Respiratory rate (breaths/min) | 23.1 (5.8) | 22.9 (5.9) | 23.2 (5.8) | 0.201 |
qSOFA ≥ 2 | 2302 (92.4) | 1103 (94.0) | 1199 (90.9)* | 0.63 (0.47–0.86) |
SIRS ≥ 2 | 1878 (75.4) | 886 (75.5) | 992 (75.2) | 0.98 (0.82–1.18) |
Diagnosis at admission | 819 (32.9) | 350 (29.8) | 469 (35.6)* | 1.30 (1.10–1.53) |