Skip to main content

Table 1 Baseline characteristics and outcomes

From: Predictors of clinical outcomes after cardiac resynchronization therapy in patients ≥75 years of age: a retrospective cohort study

 < 75 years old (n = 141)≥75 years old (n = 102)p value
Age (years)64 (10)79 (7)< 0.001
Male sex, n (%)122 (87)78 (77)0.04
Ischemic cardiomyopathy, n (%)71 (50)63 (62)0.08
Atrial fibrillation, n (%)66 (47)56 (57)0.14
Diabetes mellitus, n (%)44 (31)29 (29)0.71
CKD, n (%)62 (49)68 (72)0.001
NYHA functional class, n (%)
 I3 (2)1 (1)0.01
 II57 (40)22 (21)
 III52 (37)62 (61)
 IV ambulatory7 (5)7 (7)
 IV in hospital22 (16)10 (10)
Rescue CRT, n (%)14 (10)8 (8)0.58
Beta blocker, n (%)119 (85)78 (79)0.21
ACEI or ARB, n (%)112 (80)71 (72)0.14
Aldosterone antagonist, n (%)71 (51)36 (36)0.03
Loop diuretic, n (%)105 (75)85 (86)0.04
Ivabradine, n (%)21 (15)11 (11)0.38
Anticoagulation therapy, n (%)73 (52)59 (58)0.33
Anti-platelet agent, n (%)73 (52)55 (54)0.60
QRS morphology, n (%)
 LBBB110 (78)82 (80)0.50
 RBBB10 (7)6 (6)
 NIVCD3 (2)0
 Paced QRS18 (13)14 (14)
LVEF (%)28 (6)28 (7)0.47
CRT-D, n (%)122 (87)53 (52)< 0,001
Upgrade, n (%)41 (29)25 (25)0.43
Effectiveness, n (%)70 (50)48 (47)0.69
One-year survival124 (88)85 (83)0.31
NYHA improvement86 (61)67 (66)0.72
No admission for HF107 (76)71 (70)0.33
Complications, n in n patients (%)55 in 30 (21)27 in 15 (15)0.19
Reintervention, n (% of complications)24 (44)9 (33)0.07
Lead displacement, n (% of complications)19 (34)7 (26)0.10
Implantation failure, n (% of complications)3 (5)5 (19)0.23
Infection, n (% of complications)6 (11)3 (11)0.59
Pneumothorax, n (% of complications)2 (4)2 (7)0.74
Perforating lead, n (% of complications)01 (4)0.24
Pericardial effusion, n (% of complications)1 (2)00.39
Hematoma, n (% of complications)00NA
  1. Continuous variables are reported as medians and interquartile ranges; categorical variables are reported as numbers and percentages. ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin II receptor blocker; CKD: chronic kidney disease (defined by estimated glomerular filtration < 60 ml/mn/1.73 m2); CRT: cardiac resynchronization therapy; CRT-D: CRT with defibrillator; HF: heart failure; LBBB: left bundle branch block; LVEF: left ventricular ejection fraction; NYHA: New York Heart Association; NIVCD: nonspecific intraventricular conduction delay; RBBB: right bundle branch block
\