Table 1 Characteristic of studies included in the meta-analysis
First Author/ Year [refs] | Ethnicity /Country | Study type | Mean age at baseline, yrs | Women, % | Group description/ Patients, n | Subjects of CC/CT/TT | Subjects of C-Allele/T-Allele | NOS score |
|---|---|---|---|---|---|---|---|---|
Q.-Q. Lv/2015 [24] | Chinese/Asian | Case-control | 69 | 41.7 | Ischemic stroke/199 | 70/98/31 | 238/160 | 6 |
| Â | Â | Â | 67 | 46.5 | Control/241 | 88/116/37 | 292/190 | Â |
Bao-Sheng Zhou/2014 [25] | Chinese/Asian | Case-control | 66 | 36.3 | Ischemic stroke/542 | 160/270/112 | 382/590 | 6 |
| Â | Â | Â | 66 | 38.6 | Control/654 | 242/308/104 | 792/516 | Â |
Lihui Xiong/2012 [26] | Chinese/Asian | Case-control | 69 | 28.0 | Ischemic stroke/89 | 35/42/12 | 112/66 | 6 |
| Â | Â | Â | 68 | 27.0 | Control/102 | 46/45/11 | 137/67 | Â |
Zhang Yan/2008 [27] | Chinese/Asian | Case-control | ≥67 | NA | Ischemic stroke/105 | 22/45/38 | 89/121 | 6 |
|  |  |  | ≥67 | NA | Control/59 | 18/23/18 | 59/59 |  |
Ryuichi Kawamoto/2005 [28] | Non-Chinese/Asian | Case-control | 78 | 41.2 | Ischemic stroke/97 | 33/43/21 | 109/85 | 6 |
| Â | Â | Â | 76 | 51.0 | Control/241 | 91/110/40 | 292/190 | Â |
Jun-Hyun Yoo/2000 [29] | Non-Chinese/Asian | Case-control | 74 | 61.0 | Ischemic stroke/122 | 41/69/12 | 151/93 | 6 |
| Â | Â | Â | 72 | 60.0 | Control/217 | 77/114/26 | 268/280 | Â |
Richard D.Press/1999 [30] | Non-Chinese/Non-Asian | Case-control | 65 | 10.0 | Ischemic stroke/136 | 56/71/9 | 183/89 | 5 |
| Â | Â | Â | 67 | 42.0 | Control/52 | 28/23/1 | 79/25 | Â |
Dawn L. Harmon/1999 [31] | Non-Chinese/Non-Asian | Case-control | 79 | 52.9 | Ischemic stroke/174 | 74/73/27 | 221/127 | 5 |
| Â | Â | Â | 73 | 74.9 | Control/183 | 86/78/19 | 250/116 | Â |
K.Kostulas/1998 [32] | Non-Chinese/Non-Asian | Case-control | > 65 | NA | Ischemic stroke/62 | 34/22/6 | 90/34 | 6 |
|  |  |  | > 65 | NA | Control/62 | 25/30/7 | 80/44 |  |