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Table 1 Characteristic of studies included in the meta-analysis

From: The association of MTHFR C677T variant with increased risk of ischemic stroke in the elderly population: a meta-analysis of observational studies

First Author/ Year [refs]Ethnicity /CountryStudy typeMean age at baseline, yrsWomen, %Group description/ Patients, nSubjects of CC/CT/TTSubjects of C-Allele/T-AlleleNOS score
Q.-Q. Lv/2015 [24]Chinese/AsianCase-control6941.7Ischemic stroke/19970/98/31238/1606
   6746.5Control/24188/116/37292/190 
Bao-Sheng Zhou/2014 [25]Chinese/AsianCase-control6636.3Ischemic stroke/542160/270/112382/5906
   6638.6Control/654242/308/104792/516 
Lihui Xiong/2012 [26]Chinese/AsianCase-control6928.0Ischemic stroke/8935/42/12112/666
   6827.0Control/10246/45/11137/67 
Zhang Yan/2008 [27]Chinese/AsianCase-control≥67NAIschemic stroke/10522/45/3889/1216
   ≥67NAControl/5918/23/1859/59 
Ryuichi Kawamoto/2005 [28]Non-Chinese/AsianCase-control7841.2Ischemic stroke/9733/43/21109/856
   7651.0Control/24191/110/40292/190 
Jun-Hyun Yoo/2000 [29]Non-Chinese/AsianCase-control7461.0Ischemic stroke/12241/69/12151/936
   7260.0Control/21777/114/26268/280 
Richard D.Press/1999 [30]Non-Chinese/Non-AsianCase-control6510.0Ischemic stroke/13656/71/9183/895
   6742.0Control/5228/23/179/25 
Dawn L. Harmon/1999 [31]Non-Chinese/Non-AsianCase-control7952.9Ischemic stroke/17474/73/27221/1275
   7374.9Control/18386/78/19250/116 
K.Kostulas/1998 [32]Non-Chinese/Non-AsianCase-control> 65NAIschemic stroke/6234/22/690/346
   > 65NAControl/6225/30/780/44 
  1. NA, not applicable; NOS, Newcastle-Ottawa Scale
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