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Table 6 Statistical analysis

From: Effect of deep tissue laser therapy treatment on peripheral neuropathic pain in older adults with type 2 diabetes: a pilot randomized clinical trial

Outcome Test Group ANOVA Pre-test-Post-test Main Effect ANOVA Interaction
p-value
Pre-test vs Post-test
Quality of Life SF-36 DTLT < .001 < .001 a < 0.001
SLT = 0.194
Pain PDQ DTLT < .05 < .01 a < 0.001
SLT < 0.01
QVAS DTLT < .001 < .01 a < 0.001
SLT = 0.003
NPS DTLT < .001 < .01 a < 0.001
SLT = 0.019
Functionality TUG DTLT < .001 > .05 b  
SLT
Systemic Inflammation IL-6 DTLT < .05 > .05 b  
SLT
MCP-1 DTLT > .05 > .05 b  
SLT
RANTES DTLT > .05 > .05 b  
SLT
TNF-α DTLT > .05 > .05 b  
SLT
  1. a For these comparisons, the ANOVA interaction was significant, and unpaired t-tests were used to further explore the differences in change between the groups. The t-tests showed that there were significant differences in the pre-test-post-test mean change of the SF-36, PDQ, QVAS and NPS metrics; in each case, the change was greatest for the DTLT group – taken to be indicative of treatment effect
  2. b For these comparisons, the ANOVA interaction was not significant. The pre-test vs post-test comparison in the ANOVA suggested that the mean values of the TUG test and IL-6 serum concentration decreased from pre-test to post-test and that there were no significant pre-test-post-test changes in the mean values of MCP-1, RANTES, and TNF-α