|
Outcome
|
Test
|
Group
|
ANOVA Pre-test-Post-test Main Effect
|
ANOVA Interaction
p-value
|
Pre-test vs Post-test
|
|---|
|
Quality of Life
|
SF-36
|
DTLT
|
< .001
|
< .001 a
|
< 0.001
|
|
SLT
|
= 0.194
|
|
Pain
|
PDQ
|
DTLT
|
< .05
|
< .01 a
|
< 0.001
|
|
SLT
|
< 0.01
|
|
QVAS
|
DTLT
|
< .001
|
< .01 a
|
< 0.001
|
|
SLT
|
= 0.003
|
|
NPS
|
DTLT
|
< .001
|
< .01 a
|
< 0.001
|
|
SLT
|
= 0.019
|
|
Functionality
|
TUG
|
DTLT
|
< .001
|
> .05 b
| |
|
SLT
|
|
Systemic Inflammation
|
IL-6
|
DTLT
|
< .05
|
> .05 b
| |
|
SLT
|
|
MCP-1
|
DTLT
|
> .05
|
> .05 b
| |
|
SLT
|
|
RANTES
|
DTLT
|
> .05
|
> .05 b
| |
|
SLT
|
|
TNF-α
|
DTLT
|
> .05
|
> .05 b
| |
|
SLT
|
- a For these comparisons, the ANOVA interaction was significant, and unpaired t-tests were used to further explore the differences in change between the groups. The t-tests showed that there were significant differences in the pre-test-post-test mean change of the SF-36, PDQ, QVAS and NPS metrics; in each case, the change was greatest for the DTLT group – taken to be indicative of treatment effect
- b For these comparisons, the ANOVA interaction was not significant. The pre-test vs post-test comparison in the ANOVA suggested that the mean values of the TUG test and IL-6 serum concentration decreased from pre-test to post-test and that there were no significant pre-test-post-test changes in the mean values of MCP-1, RANTES, and TNF-α
