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Table 4 Nested Comparisons: Adjusted Logistic Regression and Negative Binomial models of Poor Self-Rated Health and ADL-IADL Index on Multimorbidity Group, SHARE 2013ā€“2015

From: Associations between prevalent multimorbidity combinations and prospective disability and self-rated health among older adults in Europe

Comparison Group

Reference Group

Poor SRH:

OR (95% CI)a

ADL-IADL Index:

IRR (95% CI)b

Addition of High Depressive Symptoms to Combination

ā€ƒ4: Hypertension + Arthritis + High Depressive Symptoms

1: Hypertension + Arthritis

1.44 (1.14ā€“1.83) *

1.33 (1.12ā€“1.59) *

ā€ƒ9: Hypertension + Diabetes Mellitus + High Depressive Symptoms

5: Hypertension + Diabetes Mellitus

1.58 (1.11ā€“2.24) *

1.74 (1.28ā€“2.36) *

ā€ƒ10: Myocardial Infarction + Hypertension + High Depressive Symptoms

6: Myocardial Infarction + Hypertension

1.24 (0.84ā€“1.84)

1.90 (1.46ā€“2.46) *

ā€ƒ7: Hypertension + Diabetes Mellitus + Arthritis + High Depressive Symptoms

8: Hypertension + Diabetes Mellitus + Arthritis

2.15 (1.33ā€“3.48) *

1.76 (1.31ā€“2.38) *

Addition of Diabetes Mellitus to Combination

ā€ƒ8: Hypertension + Diabetes Mellitusā€‰+ā€‰Arthritis

1: Hypertension + Arthritis

1.12 (0.82ā€“1.54)

1.09 (0.83ā€“1.44)

ā€ƒ9: Hypertension + Diabetes Mellitusā€‰+ā€‰High Depressive Symptoms

2: Hypertension + High Depressive Symptoms

1.13 (0.80ā€“1.61)

1.42 (1.10ā€“1.83) *

ā€ƒ7: Hypertension + Diabetes Mellitusā€‰+ā€‰Arthritis + High Depressive Symptoms

4: Hypertension + Arthritis + High Depressive Symptoms

1.44 (0.94ā€“2.20)

1.30 (1.05ā€“1.61)

Addition of Arthritis to Combination

ā€ƒ4: Hypertension + Arthritisā€‰+ā€‰High Depressive Symptoms

2: Hypertension + High Depressive Symptoms

1.14 (0.88ā€“1.46)

1.12 (0.93ā€“1.33)

ā€ƒ8: Hypertension + Diabetes Mellitus + Arthritis

5: Hypertension + Diabetes Mellitus

1.13 (0.82ā€“1.56)

0.99 (0.71ā€“1.38)

ā€ƒ7: Hypertension + Diabetes Mellitus + Arthritisā€‰+ā€‰High Depressive Symptoms

9: Hypertension + Diabetes Mellitus + High Depressive Symptoms

1.42 (0.87ā€“2.32)

1.00 (0.77ā€“1.29)

Addition of Cardiovascular Conditions to Combination

ā€ƒ10: Myocardial Infarctionā€‰+ā€‰Hypertension + High Depressive Symptoms

2: Hypertension + High Depressive Symptoms

1.39 (0.96ā€“2.01)

1.35 (1.06ā€“1.72)

ā€ƒ4: Hypertensionā€‰+ā€‰Arthritis + High Depressive Symptoms

3: Arthritis + High Depressive Symptoms

1.28 (0.98ā€“1.68)

1.00 (0.84ā€“1.20)

  1. a Adjusted for baseline self-rated health, age, sex, partnered, smoking status, BMI, education, net worth
  2. b Adjusted for baseline ADL-IADL, age, sex, partnered, smoking status, BMI, education, net worth
  3. * indicates pā€‰<ā€‰0 .01
  4. ADL Activities of daily living
  5. IADL Instrumental activities of daily living
  6. SRH Self rated health
  7. The bold term is the condition that is added to the combination relative to the reference group