Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study

Table 3 Association between malondialdehyde and all-cause mortality

	HR [95% CI] for all-cause mortality
	Unadjusted model	Basic model ^a	Fully adjusted model ^b
No. of participants	1853	1853	1505
No. of events	857	857	656
No. of person years	6686.9	6686.9	5641.2
Risk at each 5 μmol /L increase in MDA	0.96 [0.86, 1.08]	0.96 [0.86, 1.08]	0.91 [0.79, 1.04]
Risk by quintiles
Quintile 1	1.00(reference)	1.00(reference)	1.00(reference)
Quintile 2	1.02 [0.82, 1.26]	1.12 [0.91, 1.39]	1.11 [0.86, 1.42]
Quintile 3	1.06 [0.86, 1.31]	1.27 [1.03, 1.56]*	1.22 [0.96, 1.56]
Quintile 4	0.85 [0.68, 1.05]	1.11 [0.89, 1.38]	1.08 [0.83, 1.40]
Quintile 5	1.02 [0.82, 1.26]	1.09 [0.88, 1.36]	0.99 [0.77, 1.28]
P-trend	0.46	0.51	0.79

HR: hazard ratio; CI: confidence interval; MDA: malondialdehyde
a. Basic model: adjusted for age (continuous), sex (men or women), and residence (urban or rural)
b. Fully adjusted model: additionally adjusted for frequent vegetable consumption (yes or no), frequent fruit consumption (yes or not), frequent meat consumption (yes or no), frequent physical exercise (yes or no), smoking (current smoker, non-current smoker), alcohol drinking (current drinker, non-current drinker), hypertension (yes or no), body mass index (continuous), glucose (< 7 mmol/L or > =7 mmol/L), total cholesterol (< 6.2 mmol/L, > = 6.2 mmol/L), triglycerides(< 2.3 mmol/L or > =2.3 mmol/L), superoxide dismutase (continuous)
*P = 0.05

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