N-terminal pro-brain natriuretic peptide levels had an independent and added ability in the evaluation of all-cause mortality in older Chinese patients with atrial fibrillation

Table 1 Patient features and their effects on all-cause mortality

Variables	Descriptions	HR^a	95 CI^a	P ^a
Demographics
Age (year) ^b	86(82–90)	1.08	1.03–1.14	0.003
Males (%)	187(85.4)	0.83	0.37–1.84	0.642
BMI (kg/m²) ^c	24.1(3.8)	0.95	0.88–1.03	0.189
Diseases
Congestive heart failure/ventricular function< 40% (%)	102(46.6)	2.45	1.39–4.33	0.002
Hypertension (%)	170(77.6)	1.30	0.63–2.66	0.476
Diabetes mellitus (%)	78(35.6)	1.95	1.14–3.34	0.015
Stroke/TIA (%)	20(9.1)	0.81	0.29–2.25	0.690
Vascular diseases (%)	51(23.3)	1.22	0.66–2.24	0.526
Clinical presentation
Heart rate (bpm) ^b	74(64–84)	1.02	1.01–1.03	0.003
SBP (mmHg) ^b	132(123–141)	1.00	0.98–1.02	0.666
DBP (mmHg) ^b	70(64–76)	0.98	0.95–1.01	0.223
Laboratory results
Hemoglobin (g/L) ^b	123.0(107.0–136.0)	0.96	0.95–0.97	< 0.001
Plasma albumin (g/L) ^c	37.7(4.2)	0.82	0.78–0.87	< 0.001
FBG (mmol/L) ^b	5.5(4.9–6.3)	1.17	1.10–1.25	< 0.001
Cholesterol (mmol/L) ^b	3.7(3.2–4.3)	0.88	0.64–1.21	0.434
HDL-c (mmol/L) ^b	1.0(0.9–1.2)	0.13	0.05–0.32	< 0.001
LDL-c (mmol/L) ^b	2.1(1.6–2.5)	0.87	0.59–1.28	0.489
Uric acid (mmol/L) ^b	352.4(270.1–441.1)	1.00	1.00–1.01	0.021
GFR (ml/min/1.73 m²) ^b	65.8(52.6–78.6)	0.97	0.96–0.98	< 0.001
NT-proBNP (pg/mL) ^b	1333.0(463.4–3101.8)	1.84	1.53–2.22	< 0.001

Notes: ^aunivariate Cox regression analyses; ^bmedian (interquartile range); ^cmean (standard deviation)
Abbreviations: HR hazard ratio, CI confidential interval, BMI body mass index, TIA transient ischemic attack, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GFR glomerular filtration rate, NT-proBNP N-terminal pro-brain natriuretic peptide

ISSN: 1471-2318