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Table 6 Association between advantaged neighborhood characteristics and risk of dementia only in women

From: Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort

Advantaged neighborhood characteristics All-type dementia (n = 517) Univariate model Multivariate modela
n HR (95% IC) p HR (95% IC) p
Median household net taxable income No limited activity space      
T1 (< 15,487) 139 1 1
T2 (15487–18,091) 125 0.97 (0.75–1.26) 0.83 0.96 (0.76–1.20) 0.70
T3 (> 18,091) 117 0.85 (0.67–1.09) 0.21 0.89 (0.70–1.14) 0.37
Limited activity space      
T1 (< 15,487) 59 1 1
T2 (15487–18,091) 45 0.73 (0.50–1.05) 0.09 0.76 (0.53–1.07) 0.11
T3 (> 18,091) 32 0.61 (0.41–0.89) 0.01 0.67 (0.44–1.02) 0.06
Proportion of people aged 60 years or over No limited activity space      
T1 (< 20.0) 145 1 1
T2 (20.0–24.7) 113 0.80 (0.61–1.04) 0.10 0.85 (0.67–1.09) 0.21
T3 (> 24.7) 123 0.84 (0.66–1.07) 0.17 0.87 (0.69–1.10) 0.24
Limited activity space      
T1 (< 20.0) 63 1 1
T2 (20.0–24.7) 30 0.59 (0.38–0.89) 0.01 0.60 (0.39–0.92) 0.02
T3 (> 24.7) 43 0.69 (0.47–0.99) 0.04 0.68 (0.48–0.96) 0.03
  1. aMarginal Cox model adjusted for study center, education level, income, occupational category, APOEε4 carrier status, diabetes, history of cardiovascular diseases, depressive symptoms and disability (IADL « budget, medication, phone »)
  2. Note: People with limited activity space = people who have need to help to go shopping, or if they are unable to move without being accompanied, or if people are confined at home or at their neighborhood