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Table 5 Association between deprived and unequal neighborhood characteristics and risk of dementia only in women

From: Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort

Deprived and unequal neighborhood characteristics All-type dementia (n = 517) Univariate model Multivariate modela
n HR (95% IC) p HR (95% IC) p
3C deprivation score No limited activity space      
T1 (most privileged) 110 1 1
T2 120 1.03 (0.78–1.35) 0.85 1.01 (0.79–1.30) 0.91
T3 (most deprived) 151 1.24 (0.97–1.60) 0.09 1.25 (0.98–1.60) 0.08
Limited activity space      
T1 (most privileged) 36 1 1
T2 40 1.07 (0.68–1.73) 0.68 1.08 (0.68–1.70) 0.76
T3 (most deprived) 60 1.49 (0.96–2.30) 0.08 1.39 (0.89–2.16) 0.15
Proportion of blue collar workers No limited activity space      
T1 (< 13.6) 135 1 1
T2 (13.6–20.8) 119 0.98 (0.74–1.29) 0.87 0.87 (0.68–1.10) 0.24
T3 (> 20.8) 127 1.06 (0.83–1.36) 0.63 0.87 (0.69–1.09) 0.23
Limited activity space      
T1 (< 13.6) 42 1 1
T2 (13.6–20.8) 39 0.92 (0.62–1.38) 0.68 0.93 (0.61–1.40) 0.72
T3 (> 20.8) 55 1.21 (0.84–1.74) 0.32 1.11 (0.78–1.60) 0.56
Proportion of households without car No limited activity space      
T1 (< 21.2) 110 1 1
T2 (21.2–29.0) 137 1.14 (0.89–1.46) 0.30 1.19 (0.96–1.49) 0.12
T3 (> 29.0) 134 1.10 (0.84–1.46) 0.49 1.11 (0.86–1.44) 0.43
Limited activity space      
T1 (< 21.2) 34 1 1
T2 (21.2–29.0) 41 1.20 (0.75–1.91) 0.46 1.29 (0.82–2.02) 0.27
T3 (> 29.0) 61 1.43 (0.91–2.25) 0.12 1.46 (0.94–2.26) 0.09
Gini index No limited activity space      
T1 (< 0.31) 113 1 1
T2 (0.31–0.35) 133 1.09 (0.84–1.41) 0.53 1.10 (0.87–1.41) 0.43
T3 (> 0.35) 135 1.04 (0.80–1.35) 0.80 1.14 (0.89–1.45) 0.30
Limited activity space      
T1 (< 0.31) 39 1 1
T2 (0.31–0.35) 47 1.25 (0.78–2.00) 0.35 1.32 (0.86–2.04) 0.22
T3 (> 0.35) 50 1.36 (0.86–2.16) 0.19 1.28 (0.82–2.01) 0.28
  1. aMarginal Cox model adjusted for study center, education level, income, occupational category, APOEε4 carrier status, diabetes, history of cardiovascular diseases, depressive symptoms and disability (IADL « budget, medication, phone »)
  2. Note: People with limited activity space = people who have need to help to go shopping, or if they are unable to move without being accompanied, or if people are confined at home or at their neighborhood