Age, years
|
78 (5)
|
77 (5)
|
81 (5)
|
Female
|
230 (66%)
|
203 (70%)
|
27 (46%)
|
White
|
283 (81%)
|
230 (79%)
|
53 (90%)
|
Education
|
Less than high school
|
19 (5%)
|
15 (5%)
|
4 (7%)
|
High school
|
68 (19%)
|
53 (18%)
|
15 (25%)
|
Some college/college
|
136 (39%)
|
119 (41%)
|
17 (29%)
|
Graduate/professional education
|
127 (36%)
|
104 (36%)
|
23 (39%)
|
Body mass index, kg/m2
|
27.2 (4.9)
|
27.0 (4.9)
|
27.9 (5.0)
|
Current smoker
|
11 (3%)
|
10 (3%)
|
1 (2%)
|
Daily alcohol use (percent yes)
|
34 (10%)
|
28 (10%)
|
6 (10%)
|
Comorbidity counta
|
2.4 (1.5)
|
2.4 (1.5)
|
2.7 (1.5)
|
CES-D score
|
9.9 (10.2)
|
9.8 (10.0)
|
10.3 (11.0)
|
Medication use
|
Antihypertensive medication
|
237 (68%)
|
194 (66%)
|
43 (73%)
|
Antidepressants
|
35 (10%)
|
29 (10%)
|
6 (10%)
|
Anti-seizure medications
|
12 (3%)
|
10 (3%)
|
2 (4%)
|
Statins
|
160 (46%)
|
131 (45%)
|
29 (49%)
|
Anxiolytics
|
42 (12%)
|
33 (11%)
|
9 (15%)
|
Antihistamines
|
35 (10%)
|
29 (10%)
|
6 (10%)
|
Opioids
|
14 (4%)
|
10 (3%)
|
4 (7%)
|
Nonsteroidal anti-inflammatory drugs
|
65 (19%)
|
51 (18%)
|
14 (24%)
|
Analgesics/antipyretics
|
82 (24%)
|
71 (25%)
|
11 (19%)
|
Cognitive function
|
Mini-Mental State Examination
|
27.7 (2.3)
|
27.8 (2.3)
|
27.5 (2.3)
|
Trail Making Test, seconds
|
Part A
|
52 (33)
|
51 (33)
|
56 (33)
|
Part B
|
123 (68)
|
120 (66)
|
140 (72)
|
Part B less A
|
74 (55)
|
72 (55)
|
84 (55)
|
Medical conditions (self-report)
|
Stroke
|
32 (9%)
|
26 (9%)
|
6 (10%)
|
Diabetes mellitus
|
47 (13%)
|
33 (11%)
|
14 (24%)
|
Hyperlipidemia
|
179 (51%)
|
148 (51%)
|
31 (53%)
|
Hypertension
|
259 (75%)
|
214 (74%)
|
45 (78%)
|
Peripheral artery disease
|
29 (8%)
|
22 (8%)
|
7 (12%)
|
History of back pain or spinal stenosis
|
138 (39%)
|
116 (40%)
|
22 (37%)
|
History of falls
|
129 (37%)
|
106 (36%)
|
23 (40%)
|
Parkinson’s disease
|
6 (2%)
|
5 (2%)
|
1 (2%)
|
Peripheral neuropathy
|
69 (21%)
|
35 (13%)
|
34 (63%)
|
Cancer, excluding skin cancer
|
81 (23%)
|
63 (22%)
|
18 (31%)
|
Physical function
|
Uses walking aid
|
36 (10%)
|
24 (8%)
|
12 (20%)
|
Physical Activity Scale for the Elderly
|
111 (69)
|
114 (70)
|
97 (61)
|
Short Physical Performance Battery
|
9.8 (2.2)
|
10.0 (2.0)
|
8.6 (2.8)
|
Gait speed at baseline, m/s
|
1.00 (0.25)
|
1.02 (0.24)
|
0.92 (0.29)
|
Falls during first year of follow-up
|
1.1 (1.7)
|
1.1 (1.8)
|
1.0 (1.4)
|
Berg Balance score
|
51 (5)
|
52 (5)
|
48 (8)
|