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Table 2 Cross-sectional associations of serum cystatin C and impaired kidney function with prevalent geriatric depressive symptoms (n = 1440)

From: Serum cystatin C, impaired kidney function, and geriatric depressive symptoms among older people living in a rural area: a population-based study

Serum cystatin C or impaired kidney function N/n Odds ratio (95% confidence interval)
Model 1a Model 2a Model 3a
Cystatin C, mg/L
 ≤ 1.00 768/119 1.00 (reference) 1.00 (reference) 1.00 (reference)
 1.01–1.25 360/79 1.43 (1.03–1.98) 1.40 (1.004–1.95) 1.41 (1.009–1.97)
 > 1.25 312/118 3.25 (2.39–4.42) 3.30 (2.40–4.50) 3.20 (2.32–4.41)
 P for trend   < 0.001 < 0.001 < 0.001
Impaired kidney function
 No 1070/176 1.00 (reference) 1.00 (reference) 1.00 (reference)
 Yes 370/140 3.07 (2.34–4.03) 3.03 (2.30–4.01) 2.95 (2.22–3.92)
  1. N/n indicates number of subjects/number of persons with depressive symptoms
  2. Abbreviations: MMSE mini-mental state examination, ADL activities of daily living
  3. aModel 1 was adjusted for age, sex, and education; model 2 was additionally adjusted for alcohol consumption, hypertension, stroke, heart disease, cataract, chronic obstructive pulmonary disease, nephritis, and arthritis; and in model 3, MMSE score and ADL-disability were added to model 2