|
Serum cystatin C or impaired kidney function
|
N/n
|
Odds ratio (95% confidence interval)
|
|---|
|
Model 1a
|
Model 2a
|
Model 3a
|
|---|
|
Cystatin C, mg/L
|
|
≤ 1.00
|
768/119
|
1.00 (reference)
|
1.00 (reference)
|
1.00 (reference)
|
|
1.01–1.25
|
360/79
|
1.43 (1.03–1.98)
|
1.40 (1.004–1.95)
|
1.41 (1.009–1.97)
|
|
> 1.25
|
312/118
|
3.25 (2.39–4.42)
|
3.30 (2.40–4.50)
|
3.20 (2.32–4.41)
|
|
P for trend
| |
< 0.001
|
< 0.001
|
< 0.001
|
|
Impaired kidney function
|
|
No
|
1070/176
|
1.00 (reference)
|
1.00 (reference)
|
1.00 (reference)
|
|
Yes
|
370/140
|
3.07 (2.34–4.03)
|
3.03 (2.30–4.01)
|
2.95 (2.22–3.92)
|
- N/n indicates number of subjects/number of persons with depressive symptoms
- Abbreviations: MMSE mini-mental state examination, ADL activities of daily living
- aModel 1 was adjusted for age, sex, and education; model 2 was additionally adjusted for alcohol consumption, hypertension, stroke, heart disease, cataract, chronic obstructive pulmonary disease, nephritis, and arthritis; and in model 3, MMSE score and ADL-disability were added to model 2
