From: Single and dual antiplatelet therapy in elderly patients of medically managed myocardial infarction
 | DAPT | Aspirin only | p a | Clopidogrel only | p b |
---|---|---|---|---|---|
 N | 390 | 549 |  | 530 |  |
 Male (%) | 49.2 | 50.6 | 0.64 | 42.8 | 0.026 |
 Age, mean (yr) | 88 | 88 | 0.31 | 89 | 0.54 |
Presentation | |||||
 NSTEMI (%) | 85.9 | 83.8 | 0.07 | 88.1 | 0.12 |
 STEMI (%) | 14.1 | 16.2 | 0.11 | 11.9 | 0.13 |
Comorbidities | |||||
 Diabetes (%) | 48.4 | 41.5 | 0.012 | 43.7 | 0.043 |
 Hypertension (%) | 27.4 | 40.1 | < 0.001 | 41.3 | < 0.001 |
 CHF (%) | 52.8 | 51.3 | 0.45 | 55.6 | 0.36 |
 PAD (%) | 5.9 | 8.5 | 0.15 | 6.1 | 0.17 |
 Chronic pulmonary disease (%) | 34.8 | 41.5 | 0.035 | 37.6 | 0.046 |
 Renal disease | 17.7 | 17.5 | 0.31 | 18.3 | 0.54 |
 Peptic ulcer disease (%) | 18.2 | 17.8 | 0.23 | 31.3 | 0.012 |
 Malignancy (%) | 7.7 | 9.2 | 0.24 | 11.1 | 0.053 |
Medications at discharge | |||||
 Statin (%) | 37.9 | 20.6 | < 0.001 | 24.9 | < 0.001 |
 ACEI/ARB (%) | 73.8 | 59.2 | < 0.001 | 61.5 | < 0.001 |
 Beta-blocker (%) | 58.2 | 40.4 | < 0.001 | 47.4 | 0.001 |
 Diuretic (%) | 69.5 | 63.9 | 0.08 | 71.9 | 0.43 |
 Proton pump inhibitor (%) | 11.8 | 15.7 | 0.09 | 38.5 | < 0.001 |
Medications in past 60Â days | |||||
 Statin (%) | 12.8 | 7.3 | 0.005 | 9.81 | 0.15 |
 ACEI/ARB (%) | 38.7 | 37.3 | 0.67 | 37.7 | 0.76 |
 Beta-blocker (%) | 23.6 | 21.5 | 0.45 | 25.7 | 0.47 |
 Diuretics (%) | 25.1 | 31.0 | 0.05 | 29.4 | 0.15 |
 Proton pump inhibitor (%) | 6.2 | 5.7 | 0.74 | 10.2 | 0.030 |