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Table 1 Basic characteristics of study subjects

From: Single and dual antiplatelet therapy in elderly patients of medically managed myocardial infarction

 

DAPT

Aspirin only

p a

Clopidogrel only

p b

 N

390

549

 

530

 

 Male (%)

49.2

50.6

0.64

42.8

0.026

 Age, mean (yr)

88

88

0.31

89

0.54

Presentation

 NSTEMI (%)

85.9

83.8

0.07

88.1

0.12

 STEMI (%)

14.1

16.2

0.11

11.9

0.13

Comorbidities

 Diabetes (%)

48.4

41.5

0.012

43.7

0.043

 Hypertension (%)

27.4

40.1

< 0.001

41.3

< 0.001

 CHF (%)

52.8

51.3

0.45

55.6

0.36

 PAD (%)

5.9

8.5

0.15

6.1

0.17

 Chronic pulmonary disease (%)

34.8

41.5

0.035

37.6

0.046

 Renal disease

17.7

17.5

0.31

18.3

0.54

 Peptic ulcer disease (%)

18.2

17.8

0.23

31.3

0.012

 Malignancy (%)

7.7

9.2

0.24

11.1

0.053

Medications at discharge

 Statin (%)

37.9

20.6

< 0.001

24.9

< 0.001

 ACEI/ARB (%)

73.8

59.2

< 0.001

61.5

< 0.001

 Beta-blocker (%)

58.2

40.4

< 0.001

47.4

0.001

 Diuretic (%)

69.5

63.9

0.08

71.9

0.43

 Proton pump inhibitor (%)

11.8

15.7

0.09

38.5

< 0.001

Medications in past 60 days

 Statin (%)

12.8

7.3

0.005

9.81

0.15

 ACEI/ARB (%)

38.7

37.3

0.67

37.7

0.76

 Beta-blocker (%)

23.6

21.5

0.45

25.7

0.47

 Diuretics (%)

25.1

31.0

0.05

29.4

0.15

 Proton pump inhibitor (%)

6.2

5.7

0.74

10.2

0.030

  1. aComparison between aspirin only and DAPT groups
  2. bComparison between clopidogrel only and DAPT groups
  3. Abbreviations, ACEI angiotensin-converting-enzyme inhibitor, ARB angiotensin receptor blocker, CHF congestive heart failure, DATP dual antiplatelet therapy, NSTEMI non-ST-elevation myocardial infarction, PAD peripheral artery disease, STEMI ST-elevation myocardial infarction