Table 1 Conclusion from the systematic review and meta-analysis on clinical and epidemiological research published in the past five years
From: Revisiting the link between cognitive decline and masticatory dysfunction
Search criteria: 1. Key word combination: (chewing OR masticat* OR “tooth loss” OR “teeth loss” OR “number of teeth”) AND (cognit* OR memory OR dement*) AND (“systematic review” OR meta-analysis) 2. Language: English 3. Publication date: 2012.10.15–2017.10.15 | |||
|---|---|---|---|
Reference | Criteria of study selection | Number of studies included | Major findings or conclusion (direct quotation) |
Tonsekar et al. 2017 [13] | Publications on the relation between periodontitis, tooth loss and dementia | Total: 8a PT:4 RT:3 | ‘The literature on chronic periodontitis and multiple tooth loss as risk factors to dementia remains inconclusive.’ |
Tada and Miura 2017 [11] | Publications that assessed associations between mastication and cognitive function, cognitive decline and dementia among population over 40 years old | Total: 33 CS:22 PT:11 | ‘Most studies point to a positive association between mastication and cognitive function, including dementia among elderly people.’ |
Wu et al. 2016 [12] | Publications that examined the effect of oral health on change in cognitive health or dementia incidence, or the publications that examined the reverse effect. | Total: 11b (all longitudinal studies) | ‘Similarly, cognitive decline was not consistently associated with greater loss of teeth or number of decayed teeth.’ |
Delwel et al. 2016 [14] | Publications about oral health and orofacial pain Comparison was made between the older people with and without dementia. | Total: 19c CS: 9 CC: 3 RCT: 1 Longitudinal: 6 | ‘……they had an equivalent number of teeth present, similar rate of edentulousness, and equivalent decayed missing filled teeth index.’ |
Cerutti- Kopplin et al. 2016 [9] | Publications on the association between oral health and cognitive function, via prospective cohort study designs | Total: 10 PT: 10 | ‘Within the limits of the quality of published evidence, this meta-analysis lends further support to the hypothesis that tooth loss is associated with an increased risk of cognitive impairment and dementia.’ |