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Table 2 Associations between the levels of Aβ, diagnosis, and ApoE genotype in different age groups

From: Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients

  Alzheimer’s Dementia/amnestic mild cognitive impairment
Age < 65 years (N = 48) Age 65–74 years (N = 110) Age 75 years and older (N = 49)
ApoE ε4 N (%) Aβ [mean (SD)] N (%) Aβ [mean (SD)] N (%) Aβ [mean (SD)] p
None 20 (41.7) 774.1 (366.0) 23 (20.9) 687.4 (285.7) 18 (36.7) 637.4 (264.4) 0.02a
Heterozygote 17 (35.4) 659.1 (238.3) 61 (55.5) 596.9 (173.8) 24 (49.0) 528.8 (123.8) 0.01a
Homozygote 11 (22.9) 547.2 (113.0) 26 (23.6) 498.9 (99.9) 7 (14.3) 433.9 (116.1) 0.37a
P   p = 0.21a   p = 0.01a   p = 0.07a  
  1. amyloid-β
  2. aKruskal-Wallis test
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