Table 2 Associations between the levels of Aβ, diagnosis, and ApoE genotype in different age groups
From: Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients
Alzheimer’s Dementia/amnestic mild cognitive impairment | |||||||
|---|---|---|---|---|---|---|---|
Age < 65 years (N = 48) | Age 65–74 years (N = 110) | Age 75 years and older (N = 49) | |||||
ApoE ε4 | N (%) | Aβ [mean (SD)] | N (%) | Aβ [mean (SD)] | N (%) | Aβ [mean (SD)] | p |
None | 20 (41.7) | 774.1 (366.0) | 23 (20.9) | 687.4 (285.7) | 18 (36.7) | 637.4 (264.4) | 0.02a |
Heterozygote | 17 (35.4) | 659.1 (238.3) | 61 (55.5) | 596.9 (173.8) | 24 (49.0) | 528.8 (123.8) | 0.01a |
Homozygote | 11 (22.9) | 547.2 (113.0) | 26 (23.6) | 498.9 (99.9) | 7 (14.3) | 433.9 (116.1) | 0.37a |
P | p = 0.21a | p = 0.01a | p = 0.07a | ||||