NORGEP-NHa List of Explicit Criteria | Freq., regular med. Only, in % | Freq., incl. PRNb medication, in % |
---|---|---|
A: Single Substance Criteria. The following should be avoided for regular use whenever possible: | ||
1. Combination analgesic with codeine/paracetamol | 0.8 | 6.8 |
2. Tricyclic antidepressants (TCAs) for depression | 0.9 | 0.9 |
3. NSAIDs | 1.1 | 7.7 |
4. First generation antihistamines | 4.5 | 6.0 |
5. Diazepam | 1.4 | 10.7 |
6. Oxazepam: Dosage >30 mg/day | 0.8 | N/A |
7. Zopiclone: Dosage >5 mg/day | 14.1 | N/A |
8. Nitrazepam | 2.8 | 3.6 |
9. Flunitrazepam | 0.3 | 0.3 |
10. Chlometiazole | 1.2 | 8.7 |
11. Regular use of hypnotics | 30.9 | N/A |
B: Combination Criteria. The following drug combinations should be avoided whenever possible: | ||
12. Warfarin + NSAIDs | 0.0 | 0.5 |
13. Warfarin + SSRI/SNRI | 1.6 | 1.6 |
14. Warfarin + ciprofloxacin/ofloxacin/ erythromycin/ clarithromycin | 0.3 | 0.5 |
15. NSAIDs/coxibs + ACE-inhibitors/AT2-antagonists | 0.2 | 1.1 |
16. NSAIDs/coxibs + diuretics | 0.6 | 3.9 |
17. NSAIDs/coxibs + glucocorticoids | 0.0 | 0.0 |
18. NSAIDs/coxibs + SSRI/SNRIs | 0.2 | 2.0 |
19. ACE-inhibitors/AT2-antagonists + potassium or potassium-sparing diuretics | 1.9 | 1.9 |
20. Beta blocking agents + cardioselective calcium antagonists | 0.0 | 0.1 |
21. Erythromycin/clarithromycin + statins | 0.1 | 0.1 |
22. Bisphosphonate + proton pump inhibitors | 1.6 | 1.7 |
23. Concomitant use of three or more psychotropic drugs | 14.5 | 41.5 |
24. Tramadol + SSRIs | 1.4 | 6.1 |
25. Metoprolol + paroxetine/fluoxetine/bupropion | 0.0 | 0.0 |
26. Metformin + ACE-inhibitors/AT2-antagonists + diuretics | 1.0 | 1.0 |
C: Deprescribing criteria. Need for continued use should be reassessed: | ||
27. Anti-psychotics | 10.3 | 14.2 |
28. Anti-depressants | 35.3 | 35.5 |
29. Urologic spasmolytics | 0.7 | 0.7 |
30. Anticholinesterase inhibitors | 5.9 | 6.0 |
31. Drugs that lower blood pressurec | 62.5 | 65.2 |
32. Bisphosphonates | 5.4 | 5.6 |
33. Statins | 12.1 | 12.1 |
34. General use of preventive medication | N/Ad | N/Ad |