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Table 2 Multivariate Logistic Analysis of Correlates of Non-Adherence to Drug Regimens (N = 400)

From: Non-adherence to medication regimens among older African-American adults

Independent variables Non-Adherence with dosage regimen
OR (95% CI)
Model 1
Non-Adherence with dosage regimen
OR (95% CI)
Model 2
Taking less - skip or forget
OR (95% CI)
Model 3
Taking less - skip or forget
OR (95% CI)
Model 4
Gender
 Female 1 1 1 1
 Male 1.16 (0.68–1.98) 1.21 (0.71–2.07) 1.59 (0.99–2.55) 1.53 (0.95–2.46)
Age
  ≥ 75 1 1 1 1
 65–74 0.69 (0.41–1.16) 0.71 (0.43–1.19) 0.79 (0.51–1.23) 0.78 (0.50–1.21)
Education
 No high school diploma 1 1 1 1
 High school diploma 0.72 (0.39–1.32) 0.73 (0.40–1.41) 0.85 (0.51–1.43) 0.92 (0.55–1.54)
Co-payment for RX
 No 1 1 1 1
 Yes 2.94 (1.59–5.26) a 2.86 (1.54–5.26) a 1.19 (0.69–2.04) 1.11 (0.65–1.89)
Memory Deficit
 Not Noticeable 1 1 1 1
 Mild to Moderate 1.27 (0.60–2.63) 1.27 (0.60–2.70) 0.87 (0.36–1.32) 0.68 (0.36–1.32)
 Severe 2.5 (1.18–5.26) b 2.63 (1.25–5.56) a 0.88 (0.46–1.69) 0.88 (0.46–1.69)
Medication Knowledge
 Factor 1 (Dosage/Purpose) 6.76 (4.24–10.8) a 7.35 (4.53–11.9) a 0.93 (0.74–1.16) 0.93 (0.73–1.17)
 Factor 2 (Side Effects/Other Instructions) 1.33 (0.99–1.78) 1.49 (1.09–2.05) b 1.28 (1.02–1.62) c 1.29 (1.03–1.64) c
Medication Duplication
 No 1 1 1 1
 Yes 1.25 (0.71–2.17) 0.97 (0.58–1.64) 1.08 (0.66–1.72) 0.87 (0.56–1.37)
PIM
 None 1 1 1 1
 At Least One 1.23 (0.70–2.32) 1.19 (0.67–2.08) 0.76 (0.47–1.23) 0.76 (0.92–1.25)
Medication Regimen Complexity Index
  < 10 1 NA 1 NA
  ≥ 10 2.02 (1.10–3.90) c - 2.43 (1.31–4.50) b -
Polypharmacy
 0–4 NA 1 NA 1
  ≥ 5 - 1.09 (0.60–1.97) - 1.66 (0.99–2.80)
-2 Log Likelihood 391.2 395.5 491.9 491.6
Nagelkerke R-Square 0.438 0.428 0.11 0.10
% of correctly predicted outcome 77% 76% 66% 66%
  1. Notes: a indicates P-value <001; b indicates P-value < .01; c indicates P-value < .05
  2. RX = Prescription medication
  3. PIM = Potentially Inappropriate medication