Table 1 Demographic and clinical characteristics at admission
Characteristics | Age < 65 years (N = 132) | Age ≥ 65 years (N = 71) | P value |
|---|---|---|---|
Demographics | |||
Male sex | 92 (69.7) | 36 (50.7) | 0.007 |
Age (years), mean (SD) | 43.67 (11.7) | 78.27 (8) | <0.001 |
Vaccination status | |||
Influenza vaccine | 3 (2.3) | 23 (41) | <0.001 |
Pneumococcal vaccination | 0 (0) | 1 (1.6) | 0.322 |
Current tobacco use | 63 (56.2) | 2 (4.8) | <0.001 |
Heavy drinker (> 80 mg alcohol/day) | 29 (22.3) | 6 (8.7) | 0.016 |
Clinical characteristics at admission | |||
Body temperature (°C), mean (SD) | 38.05 (1.1) | 37.82 (1.1) | 0.239 |
Respiratory rate, mean (SD) | 22.50 (6.8) | 25.06 (6.7) | 0.004 |
Heart rate, mean (SD) | 108.43 (21) | 97.70 (17.6) | <0.001 |
Altered mental status | 3 (2.2) | 12 (16.9) | <0.001 |
Systolic blood pressure < 90 mmHg | 17 (12.8) | 1 (1.4) | 0.006 |
Laboratory and radiological findings | |||
BUN >30 mg/dL | 36 (27.2) | 38 (53.5) | <0.001 |
PaO2 < 60 mmHg | 39 (29.5) | 47 (66.2) | <0.001 |
CRP (mg/dL), mean (SD) | 35.23 (18.3) | 28.53 (18.4) | 0.191 |
Multilobar pneumonia | 53 (40.1) | 22 (31.4) | 0.222 |
Pleural effusion | 29 (21.9) | 8 (11.2) | 0.059 |
Urinary antigen positive | 87 (71.3) | 51 (83.6) | 0.068 |
Antibiotic resistance | |||
Penicillin/amoxicillin | 1 (0.7) | 2 (2.9) | 0.267 |
Ceftriaxone | 0 (0) | 0 (0) | ─ |
Erythromycin | 12 (9.1) | 7 (10.2) | 0.783 |
Levofloxacin | 0 (0) | 0 (0) | ─ |
CURB-65 score | <0.001 | ||
0-I | 96 (72.7) | 4 (5.6) | |
2 | 31 (23.4) | 38 (53.5) | |
3–5 | 5 (3.7) | 29 (40.8) | |