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Table 5 Odds of use of Anxiolytics or Sedatives or at one time point given use of Anxiolytics or Sedatives at a previous time point, covariates measured at the “previous” time point, N = 1406 observations

From: Persistent use of psychotropic drugs in nursing home residents in Norway

Variables Anxiolytics Sedatives
Unadjusted Adjusted Unadjusted Adjusted
OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
Assessed at previous time point
 CDR sum of boxes 0.96 (0.94; 0.99) 0.015 0.97 (0.94; 1.01)4 0.125 0.94 (0.91; 0.97) <0.001 0.94 (0.91; 0.97)1 <0.001
 GMHR
  Good 1.31 (0.68; 2.54) 0.421    1.20 (0.65; 2.23)    
  Fairly good 1.56 (0.87; 2.81) 0.138    1.42 (0.82; 2.47) 0.560  
  Poor 1.83 (1.01; 3.30) 0.046    1.43 (0.82; 2.49) 0.209  
  Very Poor 1 -    1 0.212
 PSMS score 0.96 (0.93; 0.98) 0.002 0.96 (0.93; 0.99)3 0.016 0.95 (0.93; 0.98) -  
 NPI Agitation sub-syndrome 1.00 (0.98; 1.02) 0.964    0.99 (0.97; 1.01) 0.001   
 NPI Psychosis sub-syndrome 1.01 (0.98; 1.04) 0.451    1.00 (0.97; 1.04) 0.358   
 NPI Affective sub-syndrome 1.08 (1.05; 1.11) <0.001 1.09 (1.06; 1.12)1 <0.001 1.04 (1.01; 1.07) 0.878
0.005
1.06 (1.03; 1.09)2 <0.001
 NPI Apathy 1.01 (0.97; 1.05) 0.662    0.94 (0.90; 0.99) 0.012 0.95 (0.90; 0.996)4 0.034
Assessed at baseline
 Age 0.997 (0.98; 1.02) 0.775    1.002 (0.98; 1.02) 0.812   
 Females 1.01 (0.71; 1.44) 0.967    1.28 (0.89; 1.83) 0.182
 Education (<=10 years) 1.16 (0.81; 1.66) 0.416    0.82 (0.59; 1.15) 0.253 0.77 (0.54; 1.08)5 0.125
 Duration in NH (LN) 1.07 (0.94; 1.22) 0.292 1.12 (0.98; 1.28)5 0.101 0.91 (0.81; 1.04) 0.164   
 Nursing home size 1.01 (1.002; 1.01) 0.004 1.007 (1.002; 1.011)2 0.002 1.00 (0.999; 1.01) 0.109 1.004 (1.00; 1.008)3 0.072
 Type of nursing home unit
  RU 1 -    1 -   
  REU 0.18 (0.02; 1.83) 0.146    2.35 (0.63; 8.79) 0.206   
0.754    0.62 (0.39; 0.98) 0.041
  SCU 0.93 (0.58; 1.49)        
  OU 2.96 (0.54; 16.13) 0.209    1.67 (0.34; 8.19) 0.526   
  1. RU Regular units
  2. REU rehabilitation unit
  3. SCU special care unit for people with dementia
  4. OU other units
  5. The relative importance of each covariate in the adjusted models is included with a number after the 95% CI; lowest number has highest importance