Table 5 Odds of use of Anxiolytics or Sedatives or at one time point given use of Anxiolytics or Sedatives at a previous time point, covariates measured at the “previous” time point, N = 1406 observations

 CDR sum of boxes

0.96 (0.94; 0.99)

0.015

0.97 (0.94; 1.01)⁴

0.125

0.94 (0.91; 0.97)

<0.001

0.94 (0.91; 0.97)¹

<0.001

  Good

1.31 (0.68; 2.54)

0.421

1.20 (0.65; 2.23)

  Fairly good

1.56 (0.87; 2.81)

0.138

1.42 (0.82; 2.47)

0.560

  Poor

1.83 (1.01; 3.30)

0.046

1.43 (0.82; 2.49)

0.209

  Very Poor

1

-

1

0.212

 PSMS score

0.96 (0.93; 0.98)

0.002

0.96 (0.93; 0.99)³

0.016

0.95 (0.93; 0.98)

-

 NPI Agitation sub-syndrome

1.00 (0.98; 1.02)

0.964

0.99 (0.97; 1.01)

0.001

 NPI Psychosis sub-syndrome

1.01 (0.98; 1.04)

0.451

1.00 (0.97; 1.04)

0.358

 NPI Affective sub-syndrome

1.08 (1.05; 1.11)

<0.001

1.09 (1.06; 1.12)¹

<0.001

1.04 (1.01; 1.07)

0.878

0.005

1.06 (1.03; 1.09)²

<0.001

 NPI Apathy

1.01 (0.97; 1.05)

0.662

0.94 (0.90; 0.99)

0.012

0.95 (0.90; 0.996)⁴

0.034

 Age

0.997 (0.98; 1.02)

0.775

1.002 (0.98; 1.02)

0.812

 Females

1.01 (0.71; 1.44)

0.967

1.28 (0.89; 1.83)

0.182

 Education (<=10 years)

1.16 (0.81; 1.66)

0.416

0.82 (0.59; 1.15)

0.253

0.77 (0.54; 1.08)⁵

0.125

 Duration in NH (LN)

1.07 (0.94; 1.22)

0.292

1.12 (0.98; 1.28)⁵

0.101

0.91 (0.81; 1.04)

0.164

 Nursing home size

1.01 (1.002; 1.01)

0.004

1.007 (1.002; 1.011)²

0.002

1.00 (0.999; 1.01)

0.109

1.004 (1.00; 1.008)³

0.072

  RU

1

-

1

-

  REU

0.18 (0.02; 1.83)

0.146

2.35 (0.63; 8.79)

0.206

0.754

0.62 (0.39; 0.98)

0.041

  SCU

0.93 (0.58; 1.49)

  OU

2.96 (0.54; 16.13)

0.209

1.67 (0.34; 8.19)

0.526