Table 5 Association of the CETP rs5882 V/V genotype with lipid levels

All

I/I + I/V (n = 937)

V/V (n = 77)

P-value

r²

 HDL mean mg/dl (SD)

50.3 (13.2)

53.8 (17.0)

0.03

0.007

 LDL mean mg/dl (SD)

126.4 (38.3)

128.9 (42.6)

0.62

0.005

 Triglycerides mean mg/dl (SD)

128.4 (58.1)

138.5 (91.4)

0.18

0.010

Female

I/I + I/V (n = 464)

V/V (n = 39)

P-value

r²

 HDL mean mg/dl (SD)

51.7 (12.9)

56.9 (16.5)

0.02

0.011

 LDL mean mg/dl (SD)

129.2 (40.8)

132.8 (44.5)

0.94

0.001

 Triglycerides mean mg/dl (SD)

138.7 (60.6)

145.1 (86.2)

0.56

0.007

Male

I/I + I/V (n = 473)

V/V (n = 38)

P-value

r²

 HDL mean mg/dl (SD)

48.8 (13.3)

50.7 (17.3)

0.46

0.009

 LDL mean mg/dl (SD)

123.6 (35.6)

124.9 (40.6)

0.92

0.024

 Triglycerides mean mg/dl (SD)

118.3 (40.8)

131.9 (97.2)

0.19

0.018