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Table 2 Summary of outcome measures and time points of assessment in Hospital-ADL study

From: Unravelling the potential mechanisms behind hospitalization-associated disability in older patients; the Hospital-Associated Disability and impact on daily Life (Hospital-ADL) cohort study protocol

  Question or instrument H1 H2 H3 P1 P2 P3
1. Medical & demographical data        
 Age Date of birth ×*      
 Gender   ×      
 Postal code   ×      
 Date and time of admission   ×*      
 Education (In accordance with Verhage, 1966 [57]) ×      
 Ethnicity Country of birth patient and parents ×      
 Marital status [18]   ×      
 Living arrangement [18, 19]   ×    ×   ×
 Medical comorbidity CCI [21] ×*      
 Severity of acute illness MEWS [22] ×* ×* ×*    
 Admission diagnosis   ×*      
2. Personal interviews/self-report data        
2.1 Cognitive functioning        
 Cognitive impairment MMSE [23] ×   × ×   ×
 Delirium CAM [24, 58] ×      
  Assessing whether: 1] the patient needs help with self-care; 2] the patient has previously undergone a delirium and; 3] the patient has a cognitive impairment [25] ×*      
2.2 Behavioral & psychosocial functioning        
 Fear of falling NRS fear of falling × × × × × ×
 Anxiety STAI-6 [31] ×   × × × ×
 Apathy GDS-15 [29] ×   × × × ×
 General self-efficacy ALCOS-12 [34]    × × ×  
 Quality of life 1] In general, how is your quality of life?; 2] How would you grade your life at this moment, with a range between 0 and 10? and; 3] Compared to one year ago, how would you rate your health in general now? [18] ×   × × × ×
  EQ-5D [20] ×   × × × ×
2.3 ADL/Physical functioning        
 Disability in ADLs Modified Katz Index Scale [16, 17] ×   × × × ×
 Independency in walking FAC [42] × × × × × ×
 Mobility Could you walk outside for 5 minutes two weeks before admission/currently? And how often did/do you do physical activity two weeks before admission/currently? [19] ×   × × × ×
 Falls Have you fallen once or more in the past (six) month(s)? If yes, how many times? [25] ×   × × × ×
 Pain NRS pain [35] × × × × × ×
 Fatigue NRS fatigue [37] × × × × × ×
 Impact of fatigue MFIS-5 [38]     × × ×
 Sleep quality PSQI [39] ×   × × × ×
 Sleep medication PSQI [39] ×   × × × ×
 Daytime sleepiness Do you currently suffer from daytime sleepiness? If yes, does this affect your daily living? × × × × × ×
 Polynocturia Do you currently suffer from polynocturia? If yes, does this affect your daily living? × × × × × ×
 Dizziness Do you currently suffer from dizziness? If yes, does this affect your daily living? × × × × × ×
 Shortness of breath Do you currently suffer from shortness of breath? If yes, does this affect your daily living? × × × ×× × ×
 Hearing impairment Do you experience difficulties with hearing, despite the use of a hearing aid? ×    ×   ×
 Vision impairment Do you experience difficulties with your vision, despite the use of glasses? ×    ×   ×
 Nutrition SNAQ [25, 41] ×   × × × ×
 Dependency Do you smoke? Do you use alcohol [19]? ×    ×   ×
 Polypharmacy Do you use five or more different medications [19]? ×    ×   ×
2.4 Health care utilization        
 Readmission Have you been hospitalized in the last (six) month(s)? If yes, for how many days? [18] ×*    × × ×
 Nursing home admission Have you had a nursing home admission in the last month? If yes, for how many weeks totally? [18]     × × ×
 Consult physiotherapist and/or occupational therapist Have you had a consultation with your physiotherapist and/or occupational therapist in the last month? If yes, how many times?     × × ×
 Consult general practitioner Have you had a consultation with your general practitioner in the last month? If yes, in the evening, night or weekend and how many times totally? [19]     × × ×
 Home care Do you use home care? If yes, care assistance and/or domestic help and how many hours per week [19]     × × ×
3. Physical performance tests        
 Handgrip strength Jamar® [5961] × × × ×   ×
 Mobility DEMMI [45] × × × ×   ×
 Agility CSR [47] × × × ×   ×
 Balance, strength, and gait SPPB [46] × × × ×   ×
 Walking distance 2MWT [49] × × × ×   ×
 Body composition BIA (Bodystat Quadscan 4000) [50] × × × ×   ×
 Activity tracker Fitbit Flex [51] × × × ×   ×
  Question or instrument H1 H2/H3 P1 P2 P3
4. Blood parameters       
 Inflammation markers CRP [52] × ×    
  WBC diff × ×    
  TNF-α [5355] × ×    
  IL-6 [5355] × ×    
  IL-8 [55] × ×    
Mortality Date of death      ×*
  1. Note: H1 = within 48 h after admission; H2 = during hospitalization on Monday, Wednesday, and/or Friday; H3 = at discharge; P1 = one month post-discharge (home visit); P2 = two months post-discharge (by telephone); P3 = three months post-discharge (home visit);
  2. ×* = Data will be obtained from medical record;
  3. CCI Charlson Comorbidity Index, MEWS Modified Early Warning Score, MMSE Mini Mental State Examination, CAM Confusion Assessment Method, NRS Numeric Rating Scale, STAI-6 State Trait Anxiety Inventory-6, GDS-15 Geriatric Depression Scale-15, ALCOS-12 Algemene Competentie Schaal-12 (General Self-Efficacy Scale), EQ-5D EuroQol-5D, FAC Functional Ambulation Categories, MFIS-5 Modified Fatigue Impact Scale-5, PSQI Pittsburgh Sleep Quality Index, SNAQ Short Nutritional Assessment, DEMMI De Morton Mobility Index, CSR Chair Sit and Reach test, SPPB Short Physical Performance Battery, 2MWT 2 Minute Walking Test, BIA Bioelectrical Impedance Analysis, CRP C-Reactive Protein, WBC diff White Blood Cell Differential, TNF-α Tumor Necrosis Factor-α, IL-6 Interleukin-6, IL-8 Interleukin-8