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Table 1 Characteristics of subjects according to MetS (N = 695)

From: The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people

Characteristics Total (N = 695) Men (N = 220) Women (N = 475)
MetS (N = 65) Non-MetS (N = 630) P MetS (N = 7) Non-MetS (N = 213) P MetS (N = 58) Non-MetS (N = 417) P
Age (years) 93.3 ± 3.0 93.6 ± 3.2 0.532 92.7 ± 2.8 93.3 ± 3.1 0.606 93.4 ± 3.1 93.7 ± 3.3 0.505
Women (%) 89.2 66.2 <0.001 - - - - - -
BMI (kg/m2) 22.3 ± 3.3 18.9 ± 3.6 <0.001 23.8 ± 4.5 19.6 ± 3.8 0.004 22.2 ± 3.1 18.6 ± 3.4 <0.001
WC (cm) 87.8 ± 5.2 76.5 ± 7.9 <0.001 92.1 ± 2.5 78.3 ± 7.3 <0.001 87.2 ± 5.2 75.6 ± 8.1 <0.001
SBP (mm Hg) 156 ± 18.2 138 ± 23.3 <0.001 152.9 ± 11.1 137.6 ± 20.3 0.049 156.8 ± 18.9 139.3 ± 24.7 <0.001
DBP (mm Hg) 78.4 ± 15.1 72.0 ± 11.6 <0.001 77.1 ± 7.6 73.1 ± 11.2 0.345 78.5 ± 15.8 71.4 ± 11.7 0.001
FPG (mmol/L) 5.1 ± 2.1 4.4 ± 1.3 <0.001 7.4 ± 2.8 4.5 ± 1.5 <0.001 4.9 ± 1.8 4.3 ± 1.2 0.022
TC (mom/L) 4.5 ± 1.0 4.6 ± 2.0 0.930 4.1 ± 1.1 5.3 ± 2.6 0.874 4.5 ± 1.0 4.2 ± 0.8 <0.001
TG (mmol/L) 2.0 ± 1.1 1.2 ± 0.6 <0.001 1.9 ± 1.0 1.0 ± 0.4 <0.001 2.1 ± 1.2 1.2 ± 0.6 <0.001
LDL-C (mmol/L) 2.6 ± 0.7 2.2 ± 0.6 <0.001 2.5 ± 0.7 2.1 ± 0.5 0.079 2.6 ± 0.7 2.3 ± 0.6 <0.001
HDL-C (mmol/L) 1.4 ± 0.5 1.6 ± 0.8 0.020 1.2 ± 0.3 1.5 ± 0.7 0.179 1.4 ± 0.5 1.7 ± 0.8 0.019
SUA (mmol/L) 342.4 ± 83.4 316.3 ± 88.3 0.023 394.7 ± 31.4 350.9 ± 87.6 0.189 336.0 ± 85.6 298.6 ± 83.4 0.002
Smoking habits* (%) 35.9 43.6 0.237 85.7 69.7 0.361 29.8 30.4 0.934
Alcohol habits** (%) 14.1 27.2 0.022 28.6 39.0 0.576 12.3 21.3 0.113
Exercise habits*** (%) 36.9 41.0 0.524 14.3 42.3 0.139 39.7 40.3 0.920
Klotho G-395A Genotypes
GG (%) 81.5 69.2 0.046 85.7 72.8 0.447 81.0 67.4 0.034
GA (%) 18.5 28.9   14.3 27.2   19.0 29.7  
AA (%) 0 1.9   0 0   0 2.9  
  1. Abbreviations: BMI body mass index, DBP diastolic blood pressure, FPG fasting plasma glucose, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, MetS metabolic syndrome, SBP systolic blood pressure, SUA serum uric acid, TC total cholesterol, TG triglyceride, WC waist circumference
  2. *Indicates those who were a smoker at the time of the interview
  3. **Indicates those who still drank alcohol at least once a day at the time of the interview
  4. ***Indicates those who still did some physical exercise at least 3 time per week at the time of the interview