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Table 2 Characteristics of study population in the stratified quartiles based on the baseline level of serum uric acid

From: Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up

  Q1 (n = 233) Q2 (n = 232) Q3 (n = 200) Q4 (n = 200) P
Age (years) 69.5 ± 10.1 69.2 ± 9.9 67.4 ± 9.7* 69.6 ± 10.7 0.102
Men (n, %) 79 (33.0) 107 (46.1)** 127 (63.5)** 142 (71.0)** <0.001
Hypertension duration (years) 8.6 ± 8.2 9.0 ± 8.8 10.1 ± 8.3* 11.4 ± 9.8** <0.001
Diabetes (n, %) 75 (32.2) 69 (29.7) 59 (29.5) 60 (30.0) 0.921
Body mass index (kg/m2) 24.3 ± 3.7 24.2 ± 3.4 25.1 ± 3.3* 25.5 ± 3.8** <0.001
Administration of statins (n, %) 179 (76.8) 183 (78.9) 168 (84.0) 155 (77.5) 0.266
Antihypertensive therapeutic intensity score 0.9 ± 0.8 0.9 ± 0.8 0.9 ± 0.8 1.2 ± 0.9** <0.001
Systolic blood pressure (mmHg) 145.9 ± 18.4 146.2 ± 18.7 144.9 ± 19.7 147.3 ± 20.1 0.673
Diastolic blood pressure (mmHg) 79.1 ± 12.8 79.6 ± 12.6 80.3 ± 12.7 80.7 ± 12.8 0.582
Fasting blood glucose (mmol/L) 6.04 ± 1.98 5.72 ± 1.62 5.74 ± 1.46 5.58 ± 1.38* 0.027
Triacylglycerol (mmol/L) 1.48 ± 1.18 1.62 ± 1.25 1.75 ± 1.16* 1.90 ± 1.07** 0.004
Total cholesterol (mmol/L) 4.95 ± 2.77 4.77 ± 1.21 4.87 ± 1.13 4.92 ± 1.26 0.761
HDL-C (mmol/L) 1.28 ± 0.37 1.23 ± 0.48 1.16 ± 0.33** 1.15 ± 0.35** 0.002
LDL-C (mmol/L) 2.86 ± 0.95 2.88 ± 0.99 2.94 ± 0.96 3.01 ± 1.14 0.491
Uric acid (umol/L) 230.73 ± 43.48 315.12 ± 20.06** 383.37 ± 21.13** 488.50 ± 57.64** <0.001
eGFR (ml/min per 1.73 m2) 78.46 ± 27.98 75.64 ± 27.39 75.02 ± 31.68 68.91 ± 27.70** 0.008
  1. Note: HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, eGFR estimated glomerular filtration rate. Compared with Q1 group *P < 0.05, **P < 0.01