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Table 2 Characteristics of study population in the stratified quartiles based on the baseline level of serum uric acid

From: Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up

 

Q1 (n = 233)

Q2 (n = 232)

Q3 (n = 200)

Q4 (n = 200)

P

Age (years)

69.5 ± 10.1

69.2 ± 9.9

67.4 ± 9.7*

69.6 ± 10.7

0.102

Men (n, %)

79 (33.0)

107 (46.1)**

127 (63.5)**

142 (71.0)**

<0.001

Hypertension duration (years)

8.6 ± 8.2

9.0 ± 8.8

10.1 ± 8.3*

11.4 ± 9.8**

<0.001

Diabetes (n, %)

75 (32.2)

69 (29.7)

59 (29.5)

60 (30.0)

0.921

Body mass index (kg/m2)

24.3 ± 3.7

24.2 ± 3.4

25.1 ± 3.3*

25.5 ± 3.8**

<0.001

Administration of statins (n, %)

179 (76.8)

183 (78.9)

168 (84.0)

155 (77.5)

0.266

Antihypertensive therapeutic intensity score

0.9 ± 0.8

0.9 ± 0.8

0.9 ± 0.8

1.2 ± 0.9**

<0.001

Systolic blood pressure (mmHg)

145.9 ± 18.4

146.2 ± 18.7

144.9 ± 19.7

147.3 ± 20.1

0.673

Diastolic blood pressure (mmHg)

79.1 ± 12.8

79.6 ± 12.6

80.3 ± 12.7

80.7 ± 12.8

0.582

Fasting blood glucose (mmol/L)

6.04 ± 1.98

5.72 ± 1.62

5.74 ± 1.46

5.58 ± 1.38*

0.027

Triacylglycerol (mmol/L)

1.48 ± 1.18

1.62 ± 1.25

1.75 ± 1.16*

1.90 ± 1.07**

0.004

Total cholesterol (mmol/L)

4.95 ± 2.77

4.77 ± 1.21

4.87 ± 1.13

4.92 ± 1.26

0.761

HDL-C (mmol/L)

1.28 ± 0.37

1.23 ± 0.48

1.16 ± 0.33**

1.15 ± 0.35**

0.002

LDL-C (mmol/L)

2.86 ± 0.95

2.88 ± 0.99

2.94 ± 0.96

3.01 ± 1.14

0.491

Uric acid (umol/L)

230.73 ± 43.48

315.12 ± 20.06**

383.37 ± 21.13**

488.50 ± 57.64**

<0.001

eGFR (ml/min per 1.73 m2)

78.46 ± 27.98

75.64 ± 27.39

75.02 ± 31.68

68.91 ± 27.70**

0.008

  1. Note: HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, eGFR estimated glomerular filtration rate. Compared with Q1 group *P < 0.05, **P < 0.01