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Table 2 Association of diabetes and eGFRcys with the Mini-Mental State Examination (MMSE) score and cognitive impairment

From: Interactive effects of diabetes and impaired kidney function on cognitive performance in old age: a population-based study

  β coefficient (95 % CI) of MMSE scorea Odds ratio (95 % CI) of cognitive impairment
Factors Model 1b Model 2b Model 1b Model 2b
Diabetes −0.09 (−0.18,−0.0004) −0.06 (−0.16, 0.03) 1.81 (1.27, 2.60) 1.75 (1.20, 2.53)
eGFRcys, ml/min/1.73 m2     
 ≥90 0 (reference) 0 (reference) 1.00 (reference) 1.00 (reference)
 60–89.9 −0.004 (−0.10, 0.09) −0.01 (−0.10, 0.08) 0.99 (0.64, 1.52) 0.98 (0.63, 1.52)
 <60 −0.15 (−0.28, −0.02) −0.15 (−0.28, −0.02) 1.32 (0.78, 2.22) 1.37 (0.80, 2.35)
p trend 0.039 0.046 0.27 0.23
  1. CI confidence interval, eGFR cys cystatin C-based estimated glomerular filtration rate, MMSE Mini-Mental State Examination
  2. aThe original MMSE score was transformed as –log (31-MMSE score)
  3. bModel 1 was adjusted for age, sex, and years of education, and model 2 was further adjusted for smoking, physical activity, alcohol drinking, body mass index, total cholesterol, hypertension, stroke, and depressive symptoms
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