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Table 4 Recently started antihypertensive drugs; comparison of number of hip fractures during exposed and unexposed person-timea

From: Risk of hip fracture among older people using antihypertensive drugs: a nationwide cohort study

 

Total cohort

By sex

Exposed person-days (14 days)

  

Women

Men

 

n

SIR (CI)

n

SIR (CI)

n

SIR (CI)

Thiazide

16

0.9 (0.5–1.5)

12

0.9 (0.5–1.6)

4

0.8 (0.2–2.2)

Loop diuretic

104

1.5 (1.3–1.9)

76

1.6 (1.2–2.0)

28

1.5 (1.0–2.1)

Beta blocker

47

1.0 (0.7–1.3)

32

1.0 (0.7–1.3)

15

1.0 (0.6–1.6)

Calcium channel blocker

38

1.0 (0.7–1.4)

30

1.1 (0.7–1.5)

8

0.8 (0.3–1.5)

ACE inhibitor

29

1.0 (0.7–1.5)

24

1.3 (0.8–1.9)

5

0.5 (0.2–1.2)

ACE inhibitor/Thiazide

2

0.4 (0.1–1.6)

2

0.6 (0.1–2.2)

0

Angiotensin II receptor blocker

11

1.0 (0.5–1.8)

11

1.0 (0.5–1.8)

0

Angiotensin II receptor blocker/Thiazide

10

0.5 (0.2–0.9)

8

0.5 (0.2–1.1)

2

0.4 (0–1.4)

  1. SIR Standardized Incidence Ratio
  2. aThe population of Norway born before 1945 and exposed to various antihypertensive drugs in 2005–2010 after 365 days wash out (exposed person-days, 14 days)